SCHEMBL21890417

SCHEMBL21890417

c1ccc(-n2c3ccccc3c3cc4c5cc6c(cc5n(-c5ccccc5)c4cc32)c2nc3ccccc3n2c2cccnc62)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 8/20 0.41
HPGD P15428 7/20 0.41
ALDH1A1 P00352 7/20 0.41
MAPT P10636 5/20 0.40
LMNA P02545 2/20 0.40
POLB P06746 2/20 0.40
HSD17B10 Q99714 2/20 0.40
TP53 P04637 1/20 0.40
ATM Q13315 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
KMT2A Q03164 4/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
MEN1 O00255 3/20 0.38
MAPK1 P28482 2/20 0.35
HTT P42858 1/20 0.35
CYP2C19 P33261 2/20 0.34
TSHR P16473 1/20 0.34
GAA P10253 1/20 0.33
HIF1A Q16665 1/20 0.33
TLR9 Q9NR96 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21890499 0.99 KDM4E (0.41) KDM4EHPGDALDH1A1MAPTLMNA
SCHEMBL21298169 0.99 KDM4E (0.41) KDM4EHPGDALDH1A1MAPTLMNA
SCHEMBL21298552 0.99 KDM4E (0.41) KDM4EHPGDALDH1A1MAPTLMNA
SCHEMBL23948624 0.91 KDM4E (0.36) KDM4EHPGDALDH1A1MAPTLMNA
SCHEMBL21890602 0.90 KDM4E (0.39) KDM4EHPGDALDH1A1MAPTLMNA
SCHEMBL21890179 0.90 ALDH1A1 (0.38) KDM4EHPGDALDH1A1MAPTLMNA
SCHEMBL24290345 0.90 KDM4E (0.41) KDM4EHPGDALDH1A1MAPTLMNA
SCHEMBL24292201 0.89 KDM4E (0.42) KDM4EHPGDALDH1A1MAPTLMNA
SCHEMBL24291027 0.89 KDM4E (0.42) KDM4EHPGDALDH1A1MAPTLMNA
SCHEMBL21890415 0.88 KDM4E (0.35) KDM4EHPGDALDH1A1MAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230068759-A1 DONOR-ACCEPTOR TYPE THERMALLY ACTIVATED DELAYED FLUORESCENT MATERIALS BASED ON IMIDAZO[1,2-F]PHENANTHRIDINE AND ANALOGUES ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY 2023-03-02 US disclosed
US-20200227656-A1 DONOR-ACCEPTOR TYPE THERMALLY ACTIVATED DELAYED FLUORESCENT MATERIALS BASED ON IMIDAZO[1,2-F]PHENANTHRIDINE AND ANALOGUES ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY 2020-07-16 US disclosed
US-10615349-B2 Donor-acceptor type thermally activated delayed fluorescent materials based on imidazo[1,2-F]phenanthridine and analogues ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2020-04-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200227656-A1 DONOR-ACCEPTOR TYPE THERMALLY ACTIVATED DELAYED FLUORESCENT MATERIALS BASED ON IMIDAZO[1,2-F]PHENANTHRIDINE AND ANALOGUES SUN2, STAU1, HELZ KDM4E 4206/4885HPGD 939/4885ALDH1A1 558/4885
US-20230068759-A1 DONOR-ACCEPTOR TYPE THERMALLY ACTIVATED DELAYED FLUORESCENT MATERIALS BASED ON IMIDAZO[1,2-F]PHENANTHRIDINE AND ANALOGUES SUN2, STAU1, HELZ KDM4E 4206/4885HPGD 939/4885ALDH1A1 558/4885
US-10615349-B2 Donor-acceptor type thermally activated delayed fluorescent materials based on imidazo[1,2-F]phenanthridine and analogues SUN2, STAU1, HELZ KDM4E 4206/4885HPGD 939/4885ALDH1A1 558/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.