Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 1/20 | 0.50 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.50 |
| ▸ | HTR5A | P47898 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 2/20 | 0.37 |
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31911 | 0.79 | PDK2 (0.67) | PDK2PDK4HTR5AGAAMAPT | |
| SCHEMBL29371027 | 0.79 | PDK2 (0.67) | PDK2PDK4HTR5AGAAMAPT | |
| SCHEMBL28706253 | 0.77 | PDK2 (0.64) | PDK2PDK4HTR5AGAAMAPT | |
| SCHEMBL14612689 | 0.75 | PDK2 (0.50) | PDK2PDK4HTR5AGAAMAPT | |
| SCHEMBL19968002 | 0.74 | HTR2A (0.40) | PDK2PDK4HTR5AKMT2ALMNA | |
| SCHEMBL18415206 | 0.74 | PDK2 (0.41) | PDK2PDK4MAPTKMT2AMEN1 | |
| SCHEMBL22481656 | 0.73 | PDK2 (0.54) | PDK2PDK4HTR5AGAAMAPT | |
| SCHEMBL9332219 | 0.73 | LMNA (0.54) | PDK2PDK4HTR5AGAAMAPT | |
| SCHEMBL29815212 | 0.73 | LMNA (0.54) | PDK2PDK4HTR5AGAAMAPT | |
| SCHEMBL15497968 | 0.71 | PDK2 (0.47) | PDK2PDK4HTR5AGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200091436-A1 | 9,10-DIHYDRO-ACRIDINE DERIVATIVE, AND PREPARATION METHOD AND USE THEREOF | NINGBO LUMILAN ADVANCED MATERIALS CO., LTD. (CN) | 2020-03-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200091436-A1 | 9,10-DIHYDRO-ACRIDINE DERIVATIVE, AND PREPARATION METHOD AND USE THEREOF | DHODH, DHRS9, QDPR | PDK2 1680/4885PDK4 1819/4885HTR5A 330/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.