Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.36 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MIF | P14174 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21891825 | 0.93 | CYP1A2 (0.46) | CYP1A2FAAHSIRT2SIRT1MEN1 | |
| SCHEMBL21891893 | 0.89 | FAAH (0.44) | CYP1A2FAAHSIRT2SIRT1MEN1 | |
| SCHEMBL21891766 | 0.86 | CYP1A2 (0.47) | CYP1A2FAAHSIRT2SIRT1MEN1 | |
| SCHEMBL21891888 | 0.81 | CYP1A2 (0.41) | CYP1A2FAAHSIRT2SIRT1MEN1 | |
| SCHEMBL23515281 | 0.80 | CYP1A2 (0.42) | CYP1A2FAAHSIRT2SIRT1MEN1 | |
| SCHEMBL21891798 | 0.76 | FAAH (0.56) | CYP1A2FAAHSIRT2SIRT1MEN1 | |
| SCHEMBL21891791 | 0.75 | L3MBTL1 (0.57) | CYP1A2FAAHSIRT2SIRT1MEN1 | |
| SCHEMBL23129807 | 0.75 | L3MBTL1 (0.57) | CYP1A2FAAHSIRT2SIRT1MEN1 | |
| SCHEMBL21891749 | 0.73 | CYP1A2 (0.43) | CYP1A2FAAHSIRT2SIRT1MEN1 | |
| SCHEMBL21892083 | 0.73 | CYP1A2 (0.45) | CYP1A2FAAHSIRT2SIRT1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10968168-B2 | Isocyanate production method | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2021-04-06 | — | — | US | disclosed |
| US-20200115327-A1 | ISOCYANATE PRODUCTION METHOD | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2020-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200115327-A1 | ISOCYANATE PRODUCTION METHOD | IDH3A, ALKBH3, CPS1 | CYP1A2 184/4885FAAH 847/4885SIRT2 861/4885 |
| US-10968168-B2 | Isocyanate production method | IDH3A, ALKBH3, CPS1 | CYP1A2 184/4885FAAH 847/4885SIRT2 861/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.