SCHEMBL21891791

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL23129807	1.00	L3MBTL1 (0.57)	L3MBTL1KMT2APOLBCYP1A2KDM4E
	SCHEMBL21891798	0.85	FAAH (0.56)	KMT2ACYP1A2ALDH1A1HPGDSIRT1
	SCHEMBL27981039	0.83	CYP1A2 (0.52)	KMT2APOLBCYP1A2ALDH1A1HPGD
	SCHEMBL21805219	0.83	ALDH1A1 (0.48)	L3MBTL1KMT2AALDH1A1HPGDMEN1
	SCHEMBL28704605	0.83	BCHE (0.58)	L3MBTL1KMT2APOLBALDH1A1HPGD
	SCHEMBL21805220	0.83	ALDH1A1 (0.48)	L3MBTL1KMT2AALDH1A1HPGDMEN1
	SCHEMBL21891858	0.83	PPID (0.52)	L3MBTL1POLBCYP1A2ALDH1A1TDP1
	SCHEMBL21802395	0.82	SIRT1 (0.54)	CYP1A2SIRT1SIRT2FAAH
	SCHEMBL3706987	0.81	L3MBTL1 (0.61)	L3MBTL1KMT2APOLBKDM4EALDH1A1
	SCHEMBL8139330	0.81	CYP1A2 (0.50)	KMT2ACYP1A2MEN1CYP3A4GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.