Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | POLB | P06746 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | ERN1 | O75460 | 3/20 | 0.41 |
| ▸ | APEX1 | P27695 | 2/20 | 0.41 |
| ▸ | GABRP | O00591 | 1/20 | 0.40 |
| ▸ | GABRD | O14764 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.40 |
| ▸ | GABRE | P78334 | 1/20 | 0.40 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.40 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24891886 | 0.88 | ALDH1A1 (0.42) | ALDH1A1POLBL3MBTL1TDP1ERN1 | |
| SCHEMBL10111667 | 0.84 | ERN1 (0.38) | ALDH1A1POLBL3MBTL1TDP1ERN1 | |
| SCHEMBL12488767 | 0.83 | GRIA1 (0.41) | ALDH1A1POLBL3MBTL1TDP1ERN1 | |
| SCHEMBL30281117 | 0.83 | GRIA1 (0.41) | ALDH1A1POLBL3MBTL1TDP1ERN1 | |
| SCHEMBL7614681 | 0.82 | ERN1 (0.37) | ALDH1A1POLBL3MBTL1TDP1ERN1 | |
| SCHEMBL10111663 | 0.82 | ERN1 (0.39) | ALDH1A1POLBL3MBTL1TDP1ERN1 | |
| SCHEMBL69934 | 0.79 | KDM4E (0.50) | ALDH1A1TDP1GABRPGABRDGABRA1 | |
| SCHEMBL12488904 | 0.79 | ALDH1A1 (0.46) | ALDH1A1POLBL3MBTL1TDP1ERN1 | |
| SCHEMBL14526673 | 0.78 | ERN1 (0.37) | ALDH1A1POLBL3MBTL1TDP1ERN1 | |
| SCHEMBL30932083 | 0.77 | GABRP (0.48) | ALDH1A1TDP1GABRPGABRDGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3838298-A2 | PSMA BINDING LIGAND-LINKER CONJUGATES AND METHODS FOR USING | Purdue Research Foundation (US) | 2021-06-23 | — | — | EP | disclosed |
| US-10624969-B2 | PSMA binding ligand-linker conjugates and methods for using | PURDUE RESEARCH FOUNDATION (US) | 2020-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10624969-B2 | PSMA binding ligand-linker conjugates and methods for using | FOLH1, KLK3, PSMA1 | ALDH1A1 2843/4885POLB 3578/4885L3MBTL1 3227/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.