Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.42 |
| ▸ | PLAU | P00749 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2190990 | 0.98 | ALDH1A1 (0.50) | ALDH1A1MAPK1L3MBTL1MAPTHPGD | |
| SCHEMBL27836744 | 0.82 | TSHR (0.43) | ALDH1A1MAPK1MAPTHPGDCA1 | |
| SCHEMBL21814404 | 0.81 | ALDH1A1 (0.54) | ALDH1A1MAPK1L3MBTL1MAPTHPGD | |
| SCHEMBL3117085 | 0.81 | CA1 (0.40) | ALDH1A1L3MBTL1KMT2ACA1CA2 | |
| SCHEMBL16285813 | 0.81 | ALDH1A1 (0.58) | ALDH1A1MAPK1L3MBTL1MAPTHPGD | |
| Hydrochloric Acid SCHEMBL11681830 | 0.81 | ALDH1A1 (0.50) | ALDH1A1MAPK1L3MBTL1MAPTHPGD | |
| SCHEMBL8377212 | 0.80 | ALDH1A1 (0.61) | ALDH1A1MAPK1L3MBTL1MAPTHPGD | |
| SCHEMBL19726788 | 0.80 | ALDH1A1 (0.61) | ALDH1A1MAPK1L3MBTL1MAPTHPGD | |
| SCHEMBL14586581 | 0.80 | ALDH1A1 (0.61) | ALDH1A1MAPK1L3MBTL1MAPTHPGD | |
| SCHEMBL8377215 | 0.80 | ALDH1A1 (0.61) | ALDH1A1MAPK1L3MBTL1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110224174-A1 | CREATINE ESTER ANTI-INFLAMMATORY COMPOUNDS AND FORMULATIONS | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 2011-09-15 | — | — | US | claimed |
| US-20090137669-A1 | CREATINE ESTER ANTI-INFLAMMATORY COMPOUNDS AND FORMULATIONS | REGENTS OF THE UNIVERSITY OF NEBRASKA, BOARD OF | 2009-05-28 | — | — | US | claimed |
| US-20080254198-A1 | Method of Preparing Creatine Ester Salts and Uses Thereof | BIO-ENGINEERED SUPPLEMENTS & NUTRITION, INC. (US) | 2008-10-16 | — | — | US | claimed |
| EP-1324760-B1 | CREATINE ESTER PRONUTRIENT COMPOUNDS AND FORMULATIONS | UNIV NEBRASKA (US) | 2007-06-20 | — | — | EP | claimed |
| EP-1688139-A1 | Creatine ester pronutrient compounds and formulations | Board of Regents of the University of Nebraska (US) | 2006-08-09 | — | — | EP | claimed |
| EP-1324760-A4 | CREATINE ESTER PRONUTRIENT COMPOUNDS AND FORMULATIONS | REGENTS OFTHE UNIVERSITY OF NE (US) | 2005-08-10 | — | — | EP | claimed |
| WO-2004071406-A2 | CREATINE ESTER ANTI-INFLAMMATORY COMPOUNDS AND FORMULATIONS | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) | 2004-08-26 | — | — | WO | claimed |
| US-20030212130-A1 | Creatine ester anti-inflammatory compounds and formulations | NEBRASKA, UNIVERSITY OF MEDICAL CENTER | 2003-11-13 | — | — | US | claimed |
| US-20030212136-A1 | Creatine ester pronutrient compounds and formulations | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 2003-11-13 | — | — | US | claimed |
| EP-1324760-A1 | CREATINE ESTER PRONUTRIENT COMPOUNDS AND FORMULATIONS | Board of Regents of the University of Nebraska (US) | 2003-07-09 | — | — | EP | claimed |
| WO-2002022135-A1 | CREATINE ESTER PRONUTRIENT COMPOUNDS AND FORMULATIONS | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) | 2002-03-21 | — | — | WO | claimed |
| US-20190247354-A1 | CREATINE ESTER ANTI-INFLAMMATORY COMPOUNDS AND FORMULATIONS | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) | 2019-08-15 | — | — | US | disclosed |
| US-20190247354-A1 | CREATINE ESTER ANTI-INFLAMMATORY COMPOUNDS AND FORMULATIONS | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) | 2019-08-15 | — | — | US | disclosed |
| US-10206897-B2 | Creatine ester anti-inflammatory compounds and formulations | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) | 2019-02-19 | — | — | US | disclosed |
| US-10206897-B2 | Creatine ester anti-inflammatory compounds and formulations | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) | 2019-02-19 | — | — | US | disclosed |
| WO-2004071406-A2 | CREATINE ESTER ANTI-INFLAMMATORY COMPOUNDS AND FORMULATIONS | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) | 2004-08-26 | — | — | WO | disclosed |
| US-20030212130-A1 | Creatine ester anti-inflammatory compounds and formulations | NEBRASKA, UNIVERSITY OF MEDICAL CENTER | 2003-11-13 | — | — | US | disclosed |
| US-20030212136-A1 | Creatine ester pronutrient compounds and formulations | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 2003-11-13 | — | — | US | disclosed |
| EP-1324760-A1 | CREATINE ESTER PRONUTRIENT COMPOUNDS AND FORMULATIONS | Board of Regents of the University of Nebraska (US) | 2003-07-09 | — | — | EP | disclosed |
| WO-2002022135-A1 | CREATINE ESTER PRONUTRIENT COMPOUNDS AND FORMULATIONS | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) | 2002-03-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030212130-A1 | Creatine ester anti-inflammatory compounds and formulations | CKMT1A; CKMT1B, CPT1B, CRAT | ALDH1A1 2004/4885MAPK1 1012/4885L3MBTL1 4330/4885 |
| US-20190247354-A1 | CREATINE ESTER ANTI-INFLAMMATORY COMPOUNDS AND FORMULATIONS | CKMT1A; CKMT1B, CPT1B, CRAT | ALDH1A1 2004/4885MAPK1 1012/4885L3MBTL1 4330/4885 |
| US-10206897-B2 | Creatine ester anti-inflammatory compounds and formulations | CKMT1A; CKMT1B, CPT1B, CRAT | ALDH1A1 2004/4885MAPK1 1012/4885L3MBTL1 4330/4885 |
| US-20110224174-A1 | CREATINE ESTER ANTI-INFLAMMATORY COMPOUNDS AND FORMULATIONS | CKMT1A; CKMT1B, CPT1B, CRAT | ALDH1A1 2004/4885MAPK1 1012/4885L3MBTL1 4330/4885 |
| US-20030212136-A1 | Creatine ester pronutrient compounds and formulations | CKMT1A; CKMT1B, CPT1B, PYGM | ALDH1A1 2841/4885MAPK1 3183/4885L3MBTL1 3421/4885 |
| US-20090137669-A1 | CREATINE ESTER ANTI-INFLAMMATORY COMPOUNDS AND FORMULATIONS | CKMT1A; CKMT1B, CPT1B, CRAT | ALDH1A1 2004/4885MAPK1 1012/4885L3MBTL1 4330/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.