Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CETP | P11597 | 3/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2189336 | 0.82 | ALDH1A1 (0.51) | CA1CA2ALDH1A1MAPTHPGD | |
| Hydrochloric Acid SCHEMBL2190990 | 0.81 | ALDH1A1 (0.50) | CA1CA2ALDH1A1MAPTHPGD | |
| SCHEMBL27836746 | 0.74 | TSHR (0.43) | TSHRCETPFOLH1ALDH1A1MAPT | |
| SCHEMBL9077865 | 0.74 | ALDH1A1 (0.56) | TSHRCETPFOLH1ALDH1A1MAPK1 | |
| SCHEMBL10582397 | 0.73 | CETP (0.49) | TSHRCETPFOLH1ALDH1A1MAPT | |
| SCHEMBL4966699 | 0.73 | MVD (0.36) | CA1CA2 | |
| SCHEMBL27190 | 0.72 | CA4 (0.40) | CA1CA2 | |
| SCHEMBL4110528 | 0.72 | NOS3 (0.38) | CA1CA2 | |
| SCHEMBL20712042 | 0.71 | ALDH1A1 (0.45) | TSHRCETPALDH1A1MAPTHPGD | |
| Water SCHEMBL11581073 | 0.70 | CA4 (0.39) | CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102153587-B | Method for synthesizing dibenzyloxy-phosphoryl creatinine | NANJING EAST SUNSCREEN PHARMACEUTICAL CO LTD | 2013-01-23 | — | — | CN | disclosed |
| CN-102153587-A | Method for synthesizing dibenzyloxy-phosphoryl creatinine | NANJING EAST SUNSCREEN PHARMACEUTICAL CO LTD | 2011-08-17 | — | — | CN | disclosed |