Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.41 |
| ▸ | C5AR1 | P21730 | 4/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.41 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.41 |
| ▸ | F12 | P00748 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.40 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.39 |
| ▸ | HPGDS | O60760 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2075004 | 0.93 | GPR119 (0.43) | GRM5GRM1C5AR1PDK2GPR119 | |
| SCHEMBL2075842 | 0.92 | C5AR1 (0.47) | NTRK1GRM5GRM1C5AR1PDK2 | |
| SCHEMBL2075984 | 0.85 | MEN1 (0.45) | C5AR1PDK2GPR119MAPT | |
| SCHEMBL2075003 | 0.84 | TP53 (0.43) | C5AR1GPR119HPGDSPOLBMAPT | |
| SCHEMBL2076298 | 0.84 | HPGDS (0.49) | GRM5GRM1C5AR1GPR119HPGDS | |
| SCHEMBL16036018 | 0.84 | ADORA1 (0.41) | C5AR1PARP1TNKS2PARP2F12 | |
| SCHEMBL2076536 | 0.84 | POLB (0.40) | C5AR1GPR119HPGDSPOLB | |
| SCHEMBL18493654 | 0.83 | MAPT (0.47) | C5AR1P2RX3MAPT | |
| SCHEMBL4696960 | 0.83 | PDK2 (0.36) | NTRK1PDK2ADORA1 | |
| SCHEMBL2075616 | 0.81 | MEN1 (0.47) | C5AR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020065613-A1 | MONOACYLGLYCEROL LIPASE MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2020-04-02 | — | — | WO | disclosed |