Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 7/20 | 0.50 |
| ▸ | MGLL | Q99685 | 10/20 | 0.48 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.48 |
| ▸ | PRLHR | P49683 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21893677 | 0.92 | P2RX7 (0.51) | P2RX7MGLL | |
| SCHEMBL21818705 | 0.89 | MGLL (0.56) | P2RX7MGLL | |
| SCHEMBL21894038 | 0.89 | MGLL (0.46) | P2RX7MGLL | |
| SCHEMBL21893738 | 0.89 | P2RX7 (0.50) | P2RX7MGLL | |
| SCHEMBL21894510 | 0.88 | P2RX7 (0.47) | P2RX7MGLL | |
| SCHEMBL21819385 | 0.87 | MGLL (0.58) | P2RX7MGLL | |
| SCHEMBL21893633 | 0.87 | MGLL (0.47) | P2RX7MGLL | |
| SCHEMBL21893581 | 0.86 | MGLL (0.59) | MGLL | |
| SCHEMBL21894047 | 0.86 | P2RX7 (0.49) | P2RX7MGLL | |
| SCHEMBL23872235 | 0.86 | P2RX7 (0.46) | P2RX7MGLLTRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020065613-A1 | MONOACYLGLYCEROL LIPASE MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2020-04-02 | — | — | WO | disclosed |