Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 5/20 | 0.43 |
| ▸ | MGLL | Q99685 | 6/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | NAMPT | P43490 | 3/20 | 0.41 |
| ▸ | FASN | P49327 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21893561 | 0.85 | MGLL (0.42) | KDM1AP2RX7MGLL | |
| SCHEMBL21894065 | 0.85 | P2RX7 (0.47) | P2RX7MGLLNAMPTFASN | |
| SCHEMBL21893584 | 0.85 | MGLL (0.58) | P2RX7MGLLNAMPT | |
| SCHEMBL21893709 | 0.83 | MGLL (0.50) | P2RX7MGLLNAMPT | |
| SCHEMBL21894513 | 0.83 | MGLL (0.44) | P2RX7MGLLNAMPT | |
| SCHEMBL21893831 | 0.83 | MGLL (0.44) | P2RX7MGLL | |
| SCHEMBL21893759 | 0.83 | MGLL (0.46) | P2RX7MGLLNAMPT | |
| SCHEMBL21893530 | 0.83 | P2RX7 (0.47) | P2RX7MGLLNAMPTBRD4CREBBP | |
| SCHEMBL21894036 | 0.83 | MGLL (0.58) | P2RX7MGLLNAMPT | |
| SCHEMBL21893967 | 0.82 | MGLL (0.56) | P2RX7MGLLNAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020065613-A1 | MONOACYLGLYCEROL LIPASE MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2020-04-02 | — | — | WO | disclosed |