Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 14/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 5/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21893507 | 0.88 | MGLL (0.43) | MGLLP2RX7 | |
| SCHEMBL21893719 | 0.85 | KDM1A (0.44) | MGLLP2RX7KDM1A | |
| SCHEMBL21893565 | 0.85 | MGLL (0.41) | MGLLP2RX7 | |
| SCHEMBL21893646 | 0.83 | P2RX7 (0.41) | MGLLP2RX7 | |
| SCHEMBL21893627 | 0.83 | P2RX7 (0.46) | MGLLP2RX7 | |
| SCHEMBL21893843 | 0.83 | MGLL (0.50) | MGLLP2RX7 | |
| SCHEMBL21893530 | 0.83 | P2RX7 (0.47) | MGLLP2RX7 | |
| SCHEMBL21893586 | 0.82 | MGLL (0.58) | MGLLP2RX7 | |
| SCHEMBL21893527 | 0.81 | MGLL (0.49) | MGLLP2RX7 | |
| SCHEMBL21894500 | 0.81 | MGLL (0.58) | MGLLP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020065613-A1 | MONOACYLGLYCEROL LIPASE MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2020-04-02 | — | — | WO | disclosed |