Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 6/20 | 0.49 |
| ▸ | MGLL | Q99685 | 14/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21893816 | 0.82 | MGLL (0.52) | P2RX7MGLL | |
| SCHEMBL21818287 | 0.82 | MGLL (0.51) | MGLL | |
| SCHEMBL21893792 | 0.81 | MGLL (0.44) | P2RX7MGLL | |
| SCHEMBL21893503 | 0.79 | MGLL (0.56) | P2RX7MGLL | |
| SCHEMBL21894462 | 0.78 | P2RX7 (0.48) | P2RX7MGLL | |
| SCHEMBL21893950 | 0.77 | MGLL (0.60) | P2RX7MGLL | |
| SCHEMBL21894433 | 0.77 | MGLL (0.59) | P2RX7MGLL | |
| SCHEMBL21893992 | 0.76 | MGLL (0.55) | P2RX7MGLL | |
| SCHEMBL21893537 | 0.75 | P2RX7 (0.50) | P2RX7MGLL | |
| SCHEMBL21893530 | 0.75 | P2RX7 (0.47) | P2RX7MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020065613-A1 | MONOACYLGLYCEROL LIPASE MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2020-04-02 | — | — | WO | disclosed |