Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.51 |
| ▸ | MAOB | P27338 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | IAPP | P10997 | 3/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | MMP1 | P03956 | 3/20 | 0.45 |
| ▸ | MMP2 | P08253 | 3/20 | 0.45 |
| ▸ | MMP9 | P14780 | 3/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | XBP1 | P17861 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14205237 | 0.94 | MAOA (0.56) | MAOAMAOBALDH1A1RAB9AKMT2A | |
| SCHEMBL13287417 | 0.86 | IAPP (0.62) | MAOAMAOBALDH1A1RAB9AKMT2A | |
| SCHEMBL2441249 | 0.86 | IAPP (0.62) | MAOAMAOBALDH1A1RAB9AKMT2A | |
| SCHEMBL2440214 | 0.86 | IAPP (0.62) | MAOAMAOBALDH1A1RAB9AKMT2A | |
| SCHEMBL27832635 | 0.86 | IAPP (0.62) | MAOAMAOBALDH1A1RAB9AKMT2A | |
| SCHEMBL3360114 | 0.82 | IAPP (0.58) | MAOAMAOBALDH1A1RAB9AKMT2A | |
| SCHEMBL3360109 | 0.82 | IAPP (0.58) | MAOAMAOBALDH1A1RAB9AKMT2A | |
| SCHEMBL13287444 | 0.82 | IAPP (0.58) | MAOAMAOBALDH1A1RAB9AKMT2A | |
| SCHEMBL27832650 | 0.82 | IAPP (0.58) | MAOAMAOBALDH1A1RAB9AKMT2A | |
| SCHEMBL11682651 | 0.82 | ALDH1A1 (0.73) | MAOBALDH1A1RAB9AKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2953457-B1 | ERK INHIBITORS AND USES THEREOF | CELGENE CAR LLC (BM) | 2020-04-08 | — | — | EP | disclosed |