Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.43 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.43 |
| ▸ | EDNRA | P25101 | 1/20 | 0.42 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.42 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2187905 | 0.88 | L3MBTL1 (0.49) | KDM4EKMT2ALMNATSHRALDH1A1 | |
| SCHEMBL2186762 | 0.84 | POLB (0.50) | KDM4EKMT2AALDH1A1POLBEDNRA | |
| SCHEMBL2185778 | 0.78 | POLB (0.54) | KDM4EKMT2ALMNAALDH1A1POLB | |
| SCHEMBL1974763 | 0.77 | KDM4E (0.51) | KDM4EKMT2ALMNAALDH1A1L3MBTL1 | |
| SCHEMBL2186248 | 0.77 | KDM4E (0.44) | KDM4EKMT2ALMNATSHRALDH1A1 | |
| SCHEMBL70575 | 0.77 | KMT2A (0.56) | KDM4EKMT2ALMNAALDH1A1L3MBTL1 | |
| SCHEMBL2186765 | 0.75 | KMT2A (0.43) | KDM4EKMT2ATSHRL3MBTL1POLB | |
| SCHEMBL2185780 | 0.75 | POLB (0.50) | KDM4EKMT2ALMNATSHRPOLB | |
| SCHEMBL17873718 | 0.74 | KMT2A (0.50) | KDM4EKMT2ATSHRL3MBTL1POLB | |
| SCHEMBL2467203 | 0.73 | HTT (0.64) | KDM4EKMT2ATSHRALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1578741-B1 | AROMATIC COMPOUNDS AS ANTI-INFLAMMATORY, IMMUNOMODULATORY AND ANTI-PROLIFERATORY AGENTS | 4SC AG (DE) | 2011-07-13 | — | — | EP | claimed |
| EP-1578741-B1 | AROMATIC COMPOUNDS AS ANTI-INFLAMMATORY, IMMUNOMODULATORY AND ANTI-PROLIFERATORY AGENTS | 4SC AG (DE) | 2011-07-13 | — | — | EP | disclosed |