Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK1 | P49759 | 1/20 | 0.47 |
| ▸ | NCF1 | P14598 | 2/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 7/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | GOT1 | P17174 | 1/20 | 0.42 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.42 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.42 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.42 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.42 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.42 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.42 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.42 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | TDO2 | P48775 | 1/20 | 0.40 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.39 |
| ▸ | SMO | Q99835 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17739111 | 0.95 | ACLY (0.44) | CLK1NCF1TRPV1MAPTGOT1 | |
| SCHEMBL17738585 | 0.89 | MEN1 (0.44) | CLK1CHEK1IDO1TDO2 | |
| SCHEMBL17738872 | 0.87 | TRPV1 (0.44) | TRPV1GOT1RPS6KB1IDO1TDO2 | |
| SCHEMBL17739170 | 0.87 | CYP2C9 (0.45) | CHEK1IDO1TDO2 | |
| SCHEMBL17738811 | 0.86 | TRPV1 (0.49) | TRPV1GOT1RPS6KB1 | |
| SCHEMBL17738569 | 0.86 | CYP3A4 (0.45) | TRPV1MAPTGOT1SMO | |
| SCHEMBL22057189 | 0.86 | TRPV1 (0.44) | TRPV1GOT1RPS6KB1IDO1TDO2 | |
| SCHEMBL17738817 | 0.86 | GOT1 (0.43) | CLK1TRPV1GOT1RPS6KB1IDO1 | |
| SCHEMBL17738881 | 0.86 | TSHR (0.47) | TRPV1MAPTGOT1 | |
| SCHEMBL17738580 | 0.86 | CYP11B1 (0.43) | IDO1TDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11130738-B2 | Pharmaceutical compound | IOMET PHARMA LTD. (GB) | 2021-09-28 | — | — | US | disclosed |
| US-20200172492-A1 | PHARMACEUTICAL COMPOUND | IOMET PHARMA LTD. (GB) | 2020-06-04 | — | — | US | disclosed |
| US-10590086-B2 | Pharmaceutical compound | IOMET PHARMA LTD. (GB) | 2020-03-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11130738-B2 | Pharmaceutical compound | IDO1, TDO2, IDO2 | CLK1 3348/4885NCF1 3371/4885TRPV1 3090/4885 |
| US-20200172492-A1 | PHARMACEUTICAL COMPOUND | IDO1, TDO2, IDO2 | CLK1 3348/4885NCF1 3371/4885TRPV1 3090/4885 |
| US-10590086-B2 | Pharmaceutical compound | IDO1, TDO2, IDO2 | CLK1 3348/4885NCF1 3371/4885TRPV1 3090/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.