Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12353945 | 0.82 | KDM4E (0.47) | KDM4ELMNAALDH1A1THRBHPGD | |
| SCHEMBL7715902 | 0.78 | KDM4E (0.52) | KDM4ELMNAALDH1A1THRBHPGD | |
| SCHEMBL301403 | 0.77 | KDM4E (0.59) | KDM4ELMNAALDH1A1THRBHPGD | |
| SCHEMBL11689296 | 0.77 | KDM4E (0.59) | KDM4ELMNAALDH1A1THRBHPGD | |
| SCHEMBL14822849 | 0.77 | KDM4E (0.59) | KDM4ELMNAALDH1A1THRBHPGD | |
| SCHEMBL5892403 | 0.76 | KDM4E (0.63) | KDM4ELMNAALDH1A1THRBHPGD | |
| SCHEMBL3372060 | 0.76 | KDM4E (0.44) | KDM4ELMNAALDH1A1THRBRAB9A | |
| SCHEMBL24220248 | 0.76 | LMNA (0.62) | KDM4ELMNAALDH1A1THRBHPGD | |
| SCHEMBL11800180 | 0.76 | ALDH1A1 (0.56) | KDM4ELMNAALDH1A1THRBHPGD | |
| SCHEMBL952719 | 0.76 | ALDH1A1 (0.56) | KDM4ELMNAALDH1A1THRBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240018288-A1 | CURABLE COMPOSITIONS WITH CROSSLINKERS FOR ADDITIVE MANUFACTURING | ALIGN TECHNOLOGY, INC. | 2024-01-18 | — | — | US | disclosed |
| US-20240016579-A1 | ADDITIVELY MANUFACTURED DENTAL ATTACHMENT PLACEMENT DEVICES USING CURABLE COMPOSITIONS | ALIGN TECHNOLOGY, INC. | 2024-01-18 | — | — | US | disclosed |
| US-20230021953-A1 | MULTI-VALENT POLYMERIZABLE COMPOSITIONS AND METHODS OF PRODUCING AND USING THE SAME | ALIGN TECHNOLOGY, INC. | 2023-01-26 | — | — | US | disclosed |
| US-20200115400-A1 | METHOD FOR PRODUCING SILICON COMPOUND, AND SILICON COMPOUND | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2020-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200115400-A1 | METHOD FOR PRODUCING SILICON COMPOUND, AND SILICON COMPOUND | SI, SIK1, CA1 | KDM4E 3666/4885LMNA 3637/4885ALDH1A1 881/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.