Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | PLG | P00747 | 1/20 | 0.34 |
| ▸ | PLAT | P00750 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.33 |
| ▸ | GABRP | O00591 | 1/20 | 0.33 |
| ▸ | GABRD | O14764 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.33 |
| ▸ | GABRE | P78334 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14656893 | 0.86 | PLG (0.32) | LMNAPLGPLATTSHRGABRP | |
| SCHEMBL14656891 | 0.77 | POLB (0.31) | POLB | |
| SCHEMBL1297406 | 0.76 | LMNA (0.39) | LMNAPLGPLATTSHRGABRP | |
| SCHEMBL3682628 | 0.74 | CES2 (0.53) | LMNAPLGPLATSMN1; SMN2SLC6A1 | |
| Cyclopropane Carboxylic Acid SCHEMBL9146910 | 0.74 | CES2 (0.53) | LMNAPLGPLATSMN1; SMN2SLC6A1 | |
| SCHEMBL17802907 | 0.72 | LMNA (0.39) | LMNAPLGPLATTSHRGABRP | |
| SCHEMBL14821407 | 0.72 | CES2 (0.58) | LMNAPLGPLATSMN1; SMN2SLC6A1 | |
| SCHEMBL12490862 | 0.72 | CES2 (0.58) | LMNAPLGPLATSMN1; SMN2SLC6A1 | |
| SCHEMBL12491884 | 0.72 | CES2 (0.58) | LMNAPLGPLATSMN1; SMN2SLC6A1 | |
| SCHEMBL12492040 | 0.72 | CES2 (0.58) | LMNAPLGPLATSMN1; SMN2SLC6A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10851131-B2 | Charge-tagged nucleotides and methods of use thereof | ILLUMINA, INC. (US) | 2020-12-01 | — | — | US | disclosed |
| US-20200123193-A1 | CHARGE-TAGGED NUCLEOTIDES AND METHODS OF USE THEREOF | ILLUMINA, INC. (US) | 2020-04-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200123193-A1 | CHARGE-TAGGED NUCLEOTIDES AND METHODS OF USE THEREOF | POLN, POLRMT, POLM | LMNA 219/4885PLG 2865/4885PLAT 3107/4885 |
| US-10851131-B2 | Charge-tagged nucleotides and methods of use thereof | POLN, POLRMT, POLM | LMNA 219/4885PLG 2865/4885PLAT 3107/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.