Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | CCR1 | P32246 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15429942 | 0.86 | SMN1; SMN2 (0.46) | SMN1; SMN2PKMCCR1CYP1A2CYP2C9 | |
| SCHEMBL15429750 | 0.86 | SMN1; SMN2 (0.46) | SMN1; SMN2PKMCCR1CYP1A2CYP2C9 | |
| SCHEMBL7339063 | 0.85 | SMN1; SMN2 (0.45) | SMN1; SMN2PKMCCR1CYP1A2CYP2C9 | |
| SCHEMBL21896240 | 0.85 | SMN1; SMN2 (0.44) | SMN1; SMN2PKMCCR1CYP1A2CYP2C9 | |
| SCHEMBL15429735 | 0.85 | SMN1; SMN2 (0.44) | SMN1; SMN2PKMCCR1CYP1A2CYP2C9 | |
| SCHEMBL7339055 | 0.85 | SMN1; SMN2 (0.45) | SMN1; SMN2PKMCCR1CYP1A2CYP2C9 | |
| SCHEMBL21142541 | 0.83 | PREP (0.43) | SMN1; SMN2PKMCYP1A2CYP2C9MEN1 | |
| SCHEMBL21142539 | 0.83 | SMN1; SMN2 (0.66) | SMN1; SMN2PKMMEN1KMT2AHTT | |
| SCHEMBL16580220 | 0.83 | SMN1; SMN2 (0.66) | SMN1; SMN2PKMMEN1KMT2AHTT | |
| SCHEMBL21898077 | 0.82 | RAB9A (0.42) | SMN1; SMN2PKMCCR1CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200123132-A1 | ANTIVIRAL COMPOUNDS | GILEAD PHARMASSET LLC | 2020-04-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200123132-A1 | ANTIVIRAL COMPOUNDS | MAVS, EIF2AK2, ZC3HAV1 | SMN1; SMN2 1564/4885PKM 2971/4885CCR1 795/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.