Triaziquone

Triaziquone

SCHEMBL21899780

CCCCCCNCC.O=C1C=C(N2CC2)C(=O)C(N2CC2)=C1N1CC1

nearest known ligand 0.35

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.35
TSHR P16473 2/20 0.34
KDM1A O60341 3/20 0.33
TP53 P04637 1/20 0.33
STAT3 P40763 1/20 0.33
HTT P42858 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
HDAC3 O15379 3/20 0.33
HDAC8 Q9BY41 3/20 0.33
NSD2 O96028 1/20 0.32
TTR P02766 1/20 0.32
DNMT1 P26358 1/20 0.32
ALDH1A1 P00352 1/20 0.32
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
EPHX1 P07099 1/20 0.31
ADH1B P00325 1/20 0.31
ADH1C P00326 1/20 0.31
ADH1A P07327 1/20 0.31
ADH4 P08319 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Triaziquone SCHEMBL8820777 0.88 EPHX1 (0.42) MAPTTP53STAT3HTTSMN1; SMN2
Triaziquone SCHEMBL22118274 0.85 MAPT (0.40) MAPTTP53STAT3HTTSMN1; SMN2
Octadecylamine SCHEMBL11308593 0.82 DNM1 (0.38) MAPTTSHRTP53STAT3HTT
Triaziquone SCHEMBL7938206 0.82 LMNA (0.38) MAPTTSHRTP53STAT3HTT
Triaziquone SCHEMBL11313349 0.81 TP53 (0.35) MAPTTP53STAT3HTTSMN1; SMN2
Triaziquone SCHEMBL5494678 0.80 PLK1 (0.38) MAPTSMN1; SMN2DNMT1ALDH1A1MEN1
Tetrabuthylammonium SCHEMBL9397471 0.80 SLC22A1 (0.36) MAPTTSHRTP53STAT3HTT
Triaziquone SCHEMBL11793180 0.80 TP53 (0.36) MAPTTSHRTP53STAT3HTT
Triaziquone SCHEMBL20544204 0.78 PPARG (0.46) TSHRALDH1A1MEN1KMT2A
Triaziquone SCHEMBL9016942 0.78 PPARG (0.46) TSHRALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3645496-A1 ALKOXYLATION OF HYDROXY ACIDS BASF SE (DE) 2020-05-06 EP disclosed
CN-110785395-A Alkoxylation of hydroxy acids 巴斯夫欧洲公司 2020-02-11 CN disclosed
CN-107257816-B Modification of alkyl polyalkylene glycols with epoxides 巴斯夫欧洲公司 2020-01-03 CN disclosed