Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 2/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | VHL | P40337 | 1/20 | 0.31 |
| ▸ | ELOC | Q15369 | 1/20 | 0.31 |
| ▸ | ELOB | Q15370 | 1/20 | 0.31 |
| ▸ | LTA4H | P09960 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6897708 | 0.79 | CYP2D6 (0.47) | LMNANOS1NOS3CA1CA2 | |
| SCHEMBL9013035 | 0.74 | CYP1A2 (0.51) | PPARGPPARALMNAHTTTSHR | |
| SCHEMBL13534963 | 0.69 | PRSS1 (0.44) | PPARGPPARAPRSS1PRSS2PRSS3 | |
| SCHEMBL10294039 | 0.68 | PPARG (0.40) | PPARGPPARAEPHX2PRSS1PRSS2 | |
| SCHEMBL12929939 | 0.68 | EPHX2 (0.47) | PPARGPPARAEPHX2PRSS1PRSS2 | |
| SCHEMBL41775 | 0.66 | TSHR (0.67) | PPARGPPARAPRSS1PRSS2PRSS3 | |
| SCHEMBL22426890 | 0.65 | SLC6A2 (0.33) | LMNAHTT | |
| SCHEMBL358742 | 0.64 | ESR1 (0.65) | PPARGPPARAEPHX2PRSS1PRSS2 | |
| SCHEMBL113722 | 0.64 | EPHX2 (0.61) | PPARGPPARAEPHX2LMNATSHR | |
| SCHEMBL564610 | 0.64 | SLC6A4 (0.52) | HTTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3640242-A1 | ROCK-INHIBITING COMPOUND AND USES THEREOF | Hitgen Ltd. (CN) | 2020-04-22 | — | — | EP | disclosed |