Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22768050 | 0.84 | PTPN11 (0.33) | PTPN11 | |
| SCHEMBL21900949 | 0.75 | HDAC1 (0.34) | — | |
| SCHEMBL23199536 | 0.69 | PGK1 (0.30) | PGK1 | |
| SCHEMBL30966829 | 0.68 | PTPN11 (0.43) | PGK1PTPN11 | |
| SCHEMBL20438177 | 0.67 | PDE4D (0.34) | — | |
| SCHEMBL18534459 | 0.65 | GAA (0.46) | — | |
| SCHEMBL20438012 | 0.65 | OPRL1 (0.32) | — | |
| SCHEMBL21900957 | 0.65 | PGK1 (0.38) | PGK1 | |
| SCHEMBL22688394 | 0.63 | PGK1 (0.37) | PGK1 | |
| SCHEMBL20438055 | 0.62 | HRH4 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020081257-A1 | MODULATORS OF ALPHA-1 ANTITRYPSIN | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2020-04-23 | — | — | WO | disclosed |