Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGK1 | P00558 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21901148 | 0.81 | — | — | |
| SCHEMBL18534459 | 0.71 | GAA (0.46) | — | |
| SCHEMBL21901147 | 0.71 | MEN1 (0.30) | — | |
| SCHEMBL21901271 | 0.69 | PGK1 (0.34) | PGK1 | |
| SCHEMBL22873555 | 0.68 | CSNK2A1 (0.41) | — | |
| SCHEMBL21901152 | 0.68 | GAA (0.35) | — | |
| SCHEMBL1350225 | 0.62 | TLR7 (0.35) | — | |
| SCHEMBL20109373 | 0.59 | CYP3A4 (0.48) | — | |
| SCHEMBL22873716 | 0.59 | POLB (0.33) | — | |
| SCHEMBL11223381 | 0.59 | KCNH2 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021067584-A1 | METHODS OF TREATMENT FOR ALPHA-1 ANTITRYPSIN DEFICIENCY | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2021-04-08 | — | — | WO | disclosed |