Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.33 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13411703 | 0.86 | KDM4E (0.43) | KDM4EMAPK1HIF1ANPC1MTNR1A | |
| SCHEMBL3692879 | 0.82 | MEN1 (0.46) | MEN1KMT2APSMB5CYP2C9MTNR1A | |
| SCHEMBL12719510 | 0.80 | MEN1 (0.44) | MEN1KMT2APSMB5KDM4EHIF1A | |
| SCHEMBL15943619 | 0.80 | MEN1 (0.44) | MEN1KMT2APSMB5KDM4EHIF1A | |
| SCHEMBL9080368 | 0.80 | MEN1 (0.44) | MEN1KMT2APSMB5KDM4EHIF1A | |
| SCHEMBL16015603 | 0.79 | — | — | |
| SCHEMBL6636080 | 0.79 | — | — | |
| SCHEMBL15835816 | 0.79 | — | — | |
| SCHEMBL18908557 | 0.78 | MEN1 (0.43) | MEN1KMT2APSMB5CYP2C9TSHR | |
| SCHEMBL16197865 | 0.77 | CYP2D6 (0.52) | KMT2AKDM4EMAPK1HIF1ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3640254-A1 | HYDROPHOBIC DIACRYLAMIDE COMPOUND | Life Technologies Corporation (US) | 2020-04-22 | — | — | EP | disclosed |