SCHEMBL9080368

SCHEMBL9080368

CCC(=O)NCC(O)CO

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
PSMB5 P28074 1/20 0.37
LMNA P02545 2/20 0.36
CYP2C19 P33261 1/20 0.36
HIF1A Q16665 1/20 0.36
ALDH1A1 P00352 2/20 0.36
KDM4E B2RXH2 2/20 0.36
HPGD P15428 1/20 0.36
CYP2C9 P11712 1/20 0.35
DRD3 P35462 1/20 0.35
SLC6A3 Q01959 1/20 0.35
MTNR1A P48039 3/20 0.35
MTNR1B P49286 3/20 0.35
HTR2C P28335 2/20 0.35
EGFR P00533 1/20 0.34
SRC P12931 1/20 0.34
GAA P10253 1/20 0.33
MAPT P10636 1/20 0.33
DUSP3 P51452 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12719510 1.00 MEN1 (0.44) MEN1KMT2APSMB5LMNACYP2C19
SCHEMBL15943619 1.00 MEN1 (0.44) MEN1KMT2APSMB5LMNACYP2C19
SCHEMBL19455924 0.90 MEN1 (0.40) MEN1KMT2APSMB5LMNACYP2C19
SCHEMBL19661531 0.90 MEN1 (0.40) MEN1KMT2APSMB5LMNACYP2C19
SCHEMBL3692879 0.84 MEN1 (0.46) MEN1KMT2APSMB5LMNACYP2C19
SCHEMBL29638822 0.83 LMNA (0.40) MEN1KMT2ALMNACYP2C19HIF1A
SCHEMBL12122298 0.83 CASP2 (0.44) MEN1KMT2APSMB5LMNAALDH1A1
SCHEMBL22429690 0.82 MEN1 (0.38) MEN1KMT2APSMB5KDM4ECYP2C9
SCHEMBL22429688 0.82 MEN1 (0.38) MEN1KMT2APSMB5KDM4ECYP2C9
SCHEMBL1709105 0.82 MEN1 (0.38) MEN1KMT2APSMB5CYP2C9MTNR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103524678-B Liquid crystal elastic body composite for optical actuator and preparation method thereof 湖北大学 2016-08-31 CN claimed
CN-101344735-A Hollow toner and process of preparing the same SAMSUNG ELECTRONICS CO LTD (KR) 2009-01-14 CN claimed
US-20210300940-A1 TLR7/8 ANTAGONISTS AND USES THEREOF MERCK PATENT GMBH (DE) 2021-09-30 US disclosed
US-10745356-B2 Compositions and methods for treating tuberculosis THE BROAD INSTITUTE, INC. (US) 2020-08-18 US disclosed
US-20190284140-A1 COMPOSITIONS AND METHODS FOR TREATING TUBERCULOSIS THE BROAD INSTITUTE, INC. 2019-09-19 US disclosed
US-10251845-B2 Fatty acid cysteamine conjugates and their use as activators of autophagy CATABASIS PHARMACEUTICALS, INC. (US) 2019-04-09 US disclosed
CN-108368090-A Compounds as Immunomodulators 百时美施贵宝公司 2018-08-03 CN disclosed
EP-3340979-A1 COMPOSITIONS AND METHODS FOR DRUG SENSITIZATION OF PARASITES The Texas A&M University System (US) 2018-07-04 EP disclosed
US-20170258741-A1 FATTY ACID CYSTEAMINE CONJUGATES AND THEIR USE AS ACTIVATORS OF AUTOPHAGY CATABASIS PHARMACEUTICALS, INC. (US) 2017-09-14 US disclosed
WO-2017035438-A1 COMPOSITIONS AND METHODS FOR DRUG SENSITIZATION OF PARASITES THE TEXAS A&M UNIVERSITY SYSTEM (US) 2017-03-02 WO disclosed
CN-103524678-B Liquid crystal elastic body composite for optical actuator and preparation method thereof 湖北大学 2016-08-31 CN disclosed
CN-101013278-A Method for preparing toner and toner prepared by using the method SAMSUNG ELECTRONICS CO LTD (KR) 2007-08-08 CN disclosed
CN-101008795-A Method of preparing toner and toner prepared using the method SAMSUNG ELECTRONICS CO LTD (KR) 2007-08-01 CN disclosed
CN-1996154-A Method for preparing toner and toner prepared by using the method SAMSUNG ELECTRONICS CO LTD (KR) 2007-07-11 CN disclosed
CN-1991598-A Method for preparing toner and toner prepared by using the method SAMSUNG ELECTRONICS CO LTD (KR) 2007-07-04 CN disclosed
CN-1983042-A Method of preparing toner and toner prepared using the method SAMSUNG ELECTRONICS CO LTD (KR) 2007-06-20 CN disclosed
CN-1971433-A Method for preparing toner and toner prepared by using the method SAMSUNG ELECTRONICS CO LTD (KR) 2007-05-30 CN disclosed
CN-1971434-A Method for preparing toner and toner prepared by using the method SAMSUNG ELECTRONICS CO LTD (KR) 2007-05-30 CN disclosed
CN-1928727-A Method of preparing toner and toner prepared using the method SAMSUNG ELECTRONICS CO LTD (KR) 2007-03-14 CN disclosed
US-5514754-A POLYMERIZATION OF ACRYLIC MONOMERS, NEUTRALIZATION AND GRINDING, SEPARATION, MIXING AND CROSSLINKING AMERICAN COLLOID COMPANY (US) 1996-05-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10745356-B2 Compositions and methods for treating tuberculosis C5, IFNG, TERT MEN1 2513/4885KMT2A 3608/4885PSMB5 3200/4885
US-20170258741-A1 FATTY ACID CYSTEAMINE CONJUGATES AND THEIR USE AS ACTIVATORS OF AUTOPHAGY NDUFAB1, ATG7, HADHA MEN1 2656/4885KMT2A 1811/4885PSMB5 3680/4885
US-20190284140-A1 COMPOSITIONS AND METHODS FOR TREATING TUBERCULOSIS C5, IFNG, TERT MEN1 2513/4885KMT2A 3608/4885PSMB5 3200/4885
US-10251845-B2 Fatty acid cysteamine conjugates and their use as activators of autophagy NDUFAB1, ATG7, NLN MEN1 3093/4885KMT2A 2017/4885PSMB5 3791/4885
US-20210300940-A1 TLR7/8 ANTAGONISTS AND USES THEREOF TLR7, TLR8, TLR9 MEN1 4681/4885KMT2A 1065/4885PSMB5 3485/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.