SCHEMBL13213625

SCHEMBL13213625

CCCOP(OC1C[C@H](n2cc(C)c(=O)[nH]c2=O)O[C@@H]1COC(c1ccccc1)(c1ccc(OC)cc1)c1ccc(OC)cc1)N(C(C)C)C(C)C

nearest known ligand 0.42

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
RNASE1 P07998 1/20 0.42
TK1 P04183 3/20 0.37
TK2 O00142 2/20 0.36
TYMS P04818 1/20 0.36
TOP2A P11388 2/20 0.36
TYMP P19971 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21901667 0.97 RNASE1 (0.41) RNASE1TK1TK2TYMS
SCHEMBL6324532 0.93 RNASE1 (0.45) RNASE1TK1TK2TYMSTOP2A
SCHEMBL21901427 0.93 RNASE1 (0.40) RNASE1TK1TK2TYMS
SCHEMBL21901663 0.93 RNASE1 (0.40) RNASE1TK1TK2
SCHEMBL24115407 0.92 RNASE1 (0.40) RNASE1TK1TK2TYMSTOP2A
SCHEMBL21901419 0.92 RNASE1 (0.40) RNASE1TK1TK2TYMSTOP2A
SCHEMBL9550769 0.92 RNASE1 (0.40) RNASE1TK1TK2TYMSTOP2A
SCHEMBL22984007 0.92 RNASE1 (0.40) RNASE1TK1TK2TYMSTOP2A
SCHEMBL22872065 0.92 RNASE1 (0.40) RNASE1TK1TK2TYMSTOP2A
SCHEMBL13901245 0.92 RNASE1 (0.40) RNASE1TK1TK2TYMSTOP2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100197902-A1 NUCLEIC ACID SYNTHESIZING DIMER AMIDITE AND NUCLEIC ACID SYNTHESIZING METHOD FUJITSU LIMITED (JP) 2010-08-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100197902-A1 NUCLEIC ACID SYNTHESIZING DIMER AMIDITE AND NUCLEIC ACID SYNTHESIZING METHOD ADAR, RNGTT, ATIC RNASE1 175/4885TK1 51/4885TK2 154/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.