Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 6/20 | 0.35 |
| ▸ | ACHE | P22303 | 6/20 | 0.33 |
| ▸ | CASP2 | P42575 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.32 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.32 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.32 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19321844 | 0.94 | EPHX1 (0.41) | EPHX1CASP2ZDHHC20ZDHHC2NAAA | |
| SCHEMBL19992975 | 0.93 | EPHX1 (0.43) | EPHX1CASP2ZDHHC20ZDHHC2NAAA | |
| SCHEMBL18427025 | 0.93 | EPHX1 (0.43) | EPHX1CASP2ZDHHC20ZDHHC2NAAA | |
| SCHEMBL18768946 | 0.84 | EPHX1 (0.42) | MEN1KMT2AEPHX1CASP2FAAH | |
| SCHEMBL21902153 | 0.83 | — | — | |
| SCHEMBL19453287 | 0.80 | EPHX1 (0.32) | EPHX1 | |
| SCHEMBL24238536 | 0.79 | EPHX1 (0.43) | MEN1KMT2AHTTEPHX1ACHE | |
| SCHEMBL7790310 | 0.79 | CASP2 (0.45) | MEN1KMT2AHTTEPHX1ACHE | |
| SCHEMBL19988365 | 0.79 | EPHX1 (0.43) | MEN1KMT2AHTTEPHX1ACHE | |
| SCHEMBL20848179 | 0.78 | ADRA1A (0.34) | EPHX1CASP2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230203579-A1 | NANOARRAYS AND METHODS OF USE THEREOF | FIRST-CITIZENS BANK & TRUST COMPANY | 2023-06-29 | — | — | US | disclosed |
| US-10961338-B2 | Bottlebrush polymers and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2021-03-30 | — | — | US | disclosed |
| US-20200123297-A1 | BOTTLEBRUSH POLYMERS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2020-04-23 | — | — | US | disclosed |