Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | TNF | P01375 | 1/20 | 0.39 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17100679 | 0.81 | PKM (0.55) | MAPTTP53KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL17100799 | 0.76 | TSHR (0.44) | MAPTMEN1KMT2AALDH1A1NPSR1 | |
| SCHEMBL17100667 | 0.75 | HSD11B1 (0.50) | MAPTTP53HSD17B10MEN1KMT2A | |
| SCHEMBL17100810 | 0.74 | GBA1 (0.41) | MEN1KMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL17100776 | 0.72 | ALDH1A1 (0.56) | MAPTTP53HSD17B10KMT2AALDH1A1 | |
| SCHEMBL17100797 | 0.72 | HSD11B1 (0.49) | HSD17B10MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL17100902 | 0.71 | PKM (0.49) | MAPTTP53MEN1KMT2AALDH1A1 | |
| SCHEMBL17100764 | 0.69 | PKM (0.49) | MAPTMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL17115086 | 0.69 | HTR2C (0.40) | MAPTKMT2AALDH1A1POLB | |
| SCHEMBL17101004 | 0.69 | TDP1 (0.52) | MEN1KMT2AALDH1A1SMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200140400-A1 | OXADIAZOLE COMPOUNDS | REMYND NV (BE) | 2020-05-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200140400-A1 | OXADIAZOLE COMPOUNDS | OXA1L, PSEN1, MAPT | MAPT 3/4885TP53 1588/4885HSD17B10 902/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.