Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | HAO1 | Q9UJM8 | 2/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.37 |
| ▸ | LIPE | Q05469 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 5/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21906498 | 0.86 | L3MBTL1 (0.44) | HTTL3MBTL1RXRBCYP1A2CYP2C9 | |
| SCHEMBL21907353 | 0.79 | RXRB (0.46) | L3MBTL1RXRBCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL21906696 | 0.78 | HTT (0.47) | HTTL3MBTL1RXRBMEN1KMT2A | |
| SCHEMBL21906701 | 0.78 | RXRB (0.42) | HTTL3MBTL1RXRBHAO1EGLN1 | |
| SCHEMBL21906357 | 0.77 | HTT (0.47) | HTTL3MBTL1RXRBHAO1EGLN1 | |
| SCHEMBL16838891 | 0.73 | L3MBTL1 (0.53) | HTTL3MBTL1HAO1LIPENPSR1 | |
| SCHEMBL21907351 | 0.72 | MEN1 (0.47) | HTTL3MBTL1RXRBCYP1A2CYP2C9 | |
| SCHEMBL21906532 | 0.70 | RXRB (0.45) | RXRB | |
| SCHEMBL24892941 | 0.70 | KDM4E (0.49) | HTTRXRBEGLN1NPSR1MAPT | |
| SCHEMBL3583711 | 0.68 | LTA4H (0.57) | HTTL3MBTL1HAO1CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020079039-A1 | 4-PYRAZIN-2-YLMETHYL-MORPHOLINE DERIVATIVES AND THE USE THEREOF AS MEDICAMENT | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2020-04-23 | — | — | WO | disclosed |