SCHEMBL2190675

SCHEMBL2190675

COC(=O)C1(C2C3CC4CC(C3)CC2C4)CC2C=CC1C2

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 1/20 0.33
CYP2C19 P33261 1/20 0.33
HSD11B1 P28845 1/20 0.32
EPHX2 P34913 1/20 0.31
ALDH1A1 P00352 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
SIGMAR1 Q99720 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5318552 0.82 CYP2D6 (0.33) CYP2D6CYP2C19HSD11B1EPHX2
SCHEMBL7160761 0.80 EPHX2 (0.33) CYP2D6CYP2C19EPHX2
SCHEMBL7607441 0.72
SCHEMBL7211598 0.72 CYP2D6 (0.37) CYP2D6CYP2C19ALDH1A1L3MBTL1SIGMAR1
SCHEMBL565525 0.71 HSD11B1 (0.35) CYP2D6CYP2C19HSD11B1EPHX2
SCHEMBL7703026 0.71 MAPT (0.37) CYP2D6CYP2C19SIGMAR1
SCHEMBL200115 0.70 P2RX7 (0.41) CYP2D6CYP2C19ALDH1A1
SCHEMBL18938394 0.70 P2RX7 (0.41) CYP2D6CYP2C19ALDH1A1
SCHEMBL13525792 0.69 CYP2D6 (0.35) CYP2D6CYP2C19
SCHEMBL565960 0.69 CYP2D6 (0.37) CYP2D6CYP2C19HSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110171586-A1 RESIST PROCESSING METHOD SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-07-14 US disclosed
US-6849375-B2 Photoresist monomers, polymers thereof and photoresist compositions containing the same HYNIX SEMICONDUCTOR INC. (KR) 2005-02-01 US disclosed
US-20030022101-A1 Photoresist monomers, polymers thereof and photoresist compositions containing the same INTELLECTUAL DISCOVERY CO. LTD. (KR) 2003-01-30 US disclosed