Urea

Urea

SCHEMBL219080

NC(N)=O.NCCCCC(N)CCCN

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSR P00390 1/20 0.54
RNPEP Q9H4A4 1/20 0.46
CPB2 Q96IY4 3/20 0.42
ALDH1A1 P00352 2/20 0.41
ENPEP Q07075 1/20 0.39
CYP2D6 P10635 1/20 0.39
NFKB1 P19838 1/20 0.39
GNAI3 P08754 1/20 0.38
GNAO1 P09471 1/20 0.38
GNAI1 P63096 1/20 0.38
BLM P54132 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
MEN1 O00255 1/20 0.37
PLG P00747 1/20 0.37
LMNA P02545 1/20 0.37
THRB P10828 1/20 0.37
ALOX15 P16050 1/20 0.37
SLC6A2 P23975 1/20 0.37
RECQL P46063 1/20 0.37
SLC6A3 Q01959 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL351414 0.87 NFKB1 (0.47) GSRRNPEPCPB2ENPEPNFKB1
Urea SCHEMBL1040376 0.86 GSR (0.50) GSRRNPEPCPB2ALDH1A1ENPEP
SCHEMBL11021472 0.84 DNM1 (0.50) GSRALDH1A1NFKB1BLMMEN1
SCHEMBL3792319 0.84 DNM1 (0.50) GSRALDH1A1NFKB1BLMMEN1
SCHEMBL11084535 0.84 GSR (0.44) GSRRNPEPCPB2ALDH1A1ENPEP
SCHEMBL7475389 0.84 DNM1 (0.50) GSRALDH1A1NFKB1BLMMEN1
SCHEMBL9018968 0.84 GSR (0.44) GSRRNPEPCPB2ALDH1A1ENPEP
SCHEMBL19328394 0.84 DNM1 (0.50) GSRALDH1A1NFKB1BLMMEN1
SCHEMBL350694 0.84 NFKB1 (0.50) GSRRNPEPCPB2ENPEPNFKB1
SCHEMBL15208527 0.84 GSR (0.42) GSRRNPEPALDH1A1ENPEPNFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1165713-B2 CROSSLINKABLE COATING COMPOSITIONS DSM IP ASSETS BV (NL) 2013-06-05 EP disclosed
US-8087767-B2 Inkjet ink set E. I. DU PONT DE NEMOURS AND COMPANY (US) 2012-01-03 US disclosed
EP-2001963-A1 INKJET INK SET E.I. DU PONT DE NEMOURS AND COMPANY (US) 2008-12-17 EP disclosed
WO-2007103542-A1 INKJET INK SET E. I. DU PONT DE NEMOURS AND COMPANY (US) 2007-09-13 WO disclosed
US-20070211126-A1 Inkjet ink set E. I. DU PONT DE NEMOURS AND COMPANY 2007-09-13 US disclosed
US-6555625-B1 Crosslinkable coating composition containing an autoxidisably crosslinkable organic polymer containing fatty acid residue, a vinyl polymer with acetoacetyl functional group, and a carbonyl reactive amine or hydrazine compound as crosslinker AVECIA BV (NL) 2003-04-29 US disclosed
EP-1165713-B1 CROSSLINKABLE COATING COMPOSITIONS AVECIA BV (NL) 2003-01-08 EP disclosed
EP-1165713-A1 CROSSLINKABLE COATING COMPOSITIONS Avecia B.V. (NL) 2002-01-02 EP disclosed
WO-2000056826-A1 CROSSLINKABLE COATING COMPOSITIONS AVECIA B.V. (NL) 2000-09-28 WO disclosed