Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 8/20 | 0.56 |
| ▸ | KDM4A | O75164 | 4/20 | 0.55 |
| ▸ | KDM4B | O94953 | 4/20 | 0.55 |
| ▸ | KDM5B | Q9UGL1 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | KDM5C | P41229 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.53 |
| ▸ | NCOA1 | Q15788 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21909747 | 0.87 | NPC1 (0.57) | ADORA3KDM4AKDM4BKDM5BKDM4E | |
| SCHEMBL21910766 | 0.83 | ADORA3 (0.62) | ADORA3KDM4AKDM4BKDM5BKDM4E | |
| SCHEMBL21376323 | 0.83 | L3MBTL1 (0.49) | ADORA3KDM4AKDM4BKDM5BKDM4E | |
| SCHEMBL21376581 | 0.80 | ADORA3 (0.57) | ADORA3KDM4AKDM4BKDM5BKDM4E | |
| SCHEMBL29978632 | 0.79 | L3MBTL1 (0.69) | KDM4AKDM4BKDM5BKDM4EMAPT | |
| SCHEMBL666048 | 0.79 | L3MBTL1 (0.69) | KDM4AKDM4BKDM5BKDM4EMAPT | |
| SCHEMBL666388 | 0.77 | SMN1; SMN2 (0.79) | ADORA3KDM4AKDM4BKDM5BMAPT | |
| SCHEMBL21910106 | 0.77 | ADORA3 (0.55) | ADORA3KDM4AKDM4BKDM5BKDM4E | |
| SCHEMBL663488 | 0.76 | L3MBTL1 (0.67) | KDM4AKDM4BKDM5BKDM4EMAPT | |
| SCHEMBL29977722 | 0.76 | L3MBTL1 (0.67) | KDM4AKDM4BKDM5BKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3626240-A1 | PROCESS OF PREPARATION OF A N-ARYL BENZYL SULFONAMIDE SUBSTITUTED WITH AN AMIDO GROUP | StemSynergy Therapeutics, Inc. (US) | 2020-03-25 | — | — | EP | disclosed |