Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | ADORA3 | P0DMS8 | 9/20 | 0.57 |
| ▸ | KDM4A | O75164 | 3/20 | 0.57 |
| ▸ | KDM4B | O94953 | 3/20 | 0.57 |
| ▸ | KDM5B | Q9UGL1 | 3/20 | 0.57 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | KDM5C | P41229 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | MITF | O75030 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21376536 | 0.89 | SMN1; SMN2 (0.63) | ADORA3KDM4EMAPTALDH1A1MEN1 | |
| SCHEMBL21376323 | 0.87 | L3MBTL1 (0.49) | NPC1MAPK1ALOX15USP2ADORA3 | |
| SCHEMBL21909786 | 0.87 | ADORA3 (0.56) | NPC1MAPK1ALOX15USP2ADORA3 | |
| SCHEMBL21910766 | 0.86 | ADORA3 (0.62) | NPC1MAPK1ALOX15USP2ADORA3 | |
| SCHEMBL662898 | 0.82 | SMN1; SMN2 (0.71) | NPC1MAPK1ALOX15USP2ADORA3 | |
| SCHEMBL29978107 | 0.82 | SMN1; SMN2 (0.71) | NPC1MAPK1ALOX15USP2ADORA3 | |
| SCHEMBL21376786 | 0.81 | ADORA3 (0.59) | NPC1MAPK1ALOX15USP2ADORA3 | |
| SCHEMBL26835068 | 0.79 | SMN1; SMN2 (0.46) | KDM4EMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL666388 | 0.78 | SMN1; SMN2 (0.79) | NPC1MAPK1ALOX15USP2ADORA3 | |
| SCHEMBL21910102 | 0.78 | NR0B1 (0.51) | NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3626240-A1 | PROCESS OF PREPARATION OF A N-ARYL BENZYL SULFONAMIDE SUBSTITUTED WITH AN AMIDO GROUP | StemSynergy Therapeutics, Inc. (US) | 2020-03-25 | — | — | EP | disclosed |