Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 1/20 | 0.36 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.36 |
| ▸ | LIPE | Q05469 | 7/20 | 0.33 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.30 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.30 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25426698 | 1.00 | LPL (0.36) | LPLLIPGLIPECXCR2NR1H2 | |
| SCHEMBL30510529 | 0.84 | LIPE (0.35) | LIPENR1H2NR1H3FFAR1 | |
| SCHEMBL25426051 | 0.84 | LIPE (0.35) | LIPENR1H2NR1H3FFAR1 | |
| SCHEMBL15393439 | 0.82 | LPL (0.41) | LPLLIPGLIPECXCR2FFAR1 | |
| SCHEMBL31378591 | 0.79 | LPL (0.39) | LPLLIPGCXCR2 | |
| SCHEMBL17752336 | 0.79 | LPL (0.39) | LPLLIPGCXCR2 | |
| SCHEMBL15392968 | 0.78 | LPL (0.38) | LPLLIPGLIPECXCR2 | |
| SCHEMBL21911080 | 0.78 | LPL (0.38) | LPLLIPGLIPECXCR2FFAR1 | |
| SCHEMBL30508645 | 0.78 | LPL (0.38) | LPLLIPGLIPECXCR2 | |
| SCHEMBL18865569 | 0.75 | LPL (0.36) | LPLLIPGLIPECXCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122093-A1 | REV-ERB AGONISTS FOR TH17-MEDIATED INFLAMMATORY DISORDERS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2023-06-29 | — | — | WO | disclosed |