SCHEMBL160074

SCHEMBL160074

ONc1ncnc2nc[nH]c12

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.62
CYP1A2 P05177 3/20 0.60
HIF1A Q16665 1/20 0.60
HTT P42858 5/20 0.57
LMNA P02545 6/20 0.56
PAK1 Q13153 1/20 0.56
CDK2 P24941 2/20 0.55
MKNK1 Q9BUB5 2/20 0.54
PKM P14618 1/20 0.54
HSD17B10 Q99714 1/20 0.54
BRD4 O60885 1/20 0.54
TSHR P16473 2/20 0.53
CYP2D6 P10635 1/20 0.53
MAPK1 P28482 1/20 0.53
BRAF P15056 2/20 0.53
TOP2A P11388 1/20 0.53
DRD3 P35462 1/20 0.52
PI4KA P42356 1/20 0.52
XDH P47989 1/20 0.52
LRRK2 Q5S007 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29420373 1.00 CYP3A4 (0.62) CYP3A4CYP1A2HIF1AHTTLMNA
SCHEMBL11591794 0.82 HTT (0.59) CYP3A4CYP1A2HIF1AHTTLMNA
SCHEMBL8652766 0.81 LMNA (0.54) CYP3A4CYP1A2HIF1AHTTLMNA
SCHEMBL29380490 0.80 HTT (0.62) CYP3A4CYP1A2HIF1AHTTLMNA
SCHEMBL30374699 0.80 MKNK1 (0.58) CYP3A4CYP1A2HIF1AHTTLMNA
SCHEMBL17901710 0.80 HTT (0.57) CYP3A4CYP1A2HIF1AHTTLMNA
SCHEMBL1095418 0.80 CYP1A2 (0.60) CYP3A4CYP1A2HIF1AHTTLMNA
SCHEMBL9116347 0.80 HTT (0.57) CYP3A4CYP1A2HIF1AHTTLMNA
SCHEMBL21914 0.80 HTT (0.62) CYP3A4CYP1A2HIF1AHTTLMNA
SCHEMBL18640374 0.79 CYP3A4 (0.76) CYP3A4CYP1A2HIF1AHTTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1277 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026106497-A2 FUNCTIONALIZED CIRCULAR RNA AND METHODS AND INTERMEDIATES FOR THEIR PRODUCTION SIEĆ BADAWCZA ŁUKASIEWICZ – PORT POLSKI OSRODEK ROZWOJU TECHNOLOGII (PL) 2026-05-21 WO claimed
WO-2025024123-A1 NOVEL CITICOLINE DERIVATIVES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-01-30 WO claimed
CN-118931997-A Method for synthesizing adenosine and/or uridine by three-enzyme cascade catalysis 上海飞腾医药科技有限公司 2024-11-12 CN claimed
US-20170183645-A1 COMPOSITION AND METHOD FOR DIVERSIFYING POLYPEPTIDE LIBRARIES ABZYME THERAPEUTICS LLC 2017-06-29 US claimed
US-9677067-B2 Compositions and methods for synthetic gene assembly Twist Bioscience Corporation (US) 2017-06-13 US claimed
US-20170159044-A1 COMPOSITIONS AND METHODS FOR SYNTHETIC GENE ASSEMBLY Twist Bioscience Corporation 2017-06-08 US claimed
US-20160264958-A1 COMPOSITIONS AND METHODS FOR SYNTHETIC GENE ASSEMBLY Twist Bioscience Corporation 2016-09-15 US claimed
WO-2016126987-A1 COMPOSITIONS AND METHODS FOR SYNTHETIC GENE ASSEMBLY Twist Bioscience Corporation (US) 2016-08-11 WO claimed
EP-2694524-B1 2'-O-AMINOOXYMETHYL NUCLEOSIDE DERIVATIVES FOR USE IN THE SYNTHESIS AND MODIFICATION OF NUCLEOSIDES, NUCLEOTIDES AND OLIGONUCLEOTIDES US HEALTH (US) 2016-05-18 EP claimed
US-9284343-B2 2′-O-aminooxymethyl nucleoside derivatives for use in the synthesis and modification of nucleosides, nucleotides and oligonucleotides THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2016-03-15 US claimed
US-7524942-B2 Labeled nucleotide composition AGILENT TECHNOLOGIES, INC. (US) 2009-04-28 US claimed
WO-2009032057-A2 METHOD FOR THE SELECTIVE THERAPY OF DISEASE LUBIN ADAM (US) 2009-03-12 WO claimed
US-20080124708-A1 Labeled nucleotide composition AGILENT TECHNOLOGIES, INC. 2008-05-29 US claimed
US-20070212697-A1 Labeled nucleotide composition AGILENT TECHNOLOGIES, INC. 2007-09-13 US claimed
US-5817799-A 2'-Fluorofuranosyl derivatives and methods for preparing 2'-fluoropyrimidine and 2'-fluoropurine nucleosides THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1998-10-06 US claimed
EP-0540686-B1 2'-FLUOROFURANOSYL DERIVATIVES AND NOVEL METHOD OF PREPARING 2'-FLUOROPYRIMIDINE AND 2'-FLUOROPURINE NUCLEOSIDES US COMMERCE (US) 1995-08-30 EP claimed
EP-0570514-A4 METHYLENE PHOSPHONATE NUCLEOSIDE ANALOGS AND OLIGONUCLEOTIDE ANALOGS MADE THEREFROM GILEAD SCIENCES INC (US) 1994-08-17 EP claimed
EP-0570514-A1 METHYLENE PHOSPHONATE NUCLEOSIDE ANALOGS AND OLIGONUCLEOTIDE ANALOGS MADE THEREFROM GILEAD SCIENCES, INC. (US) 1993-11-24 EP claimed
WO-1992013869-A1 METHYLENE PHOSPHONATE NUCLEOSIDE ANALOGS AND OLIGONUCLEOTIDE ANALOGS MADE THEREFROM GILEAD SCIENCES, INC. (US) 1992-08-20 WO claimed
WO-1992001700-A1 2'-FLUOROFURANOSYL DERIVATIVES AND NOVEL METHOD OF PREPARING 2'-FLUOROPYRIMIDINE AND 2'-FLUOROPURINE NUCLEOSIDES THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, U.S. DEPARTMENT OF COMMERCE (US) 1992-02-06 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080124708-A1 Labeled nucleotide composition RNGTT, RNMT, NOP2 CYP3A4 3828/4885CYP1A2 3227/4885HIF1A 4231/4885
US-20070212697-A1 Labeled nucleotide composition RNGTT, RNMT, NOP2 CYP3A4 3828/4885CYP1A2 3227/4885HIF1A 4231/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.