SCHEMBL21914399

SCHEMBL21914399

c1ccc2c(c1)oc1c(-c3cccc4c3oc3ccc(-n5c6ccccc6c6cccnc65)cc34)cccc12

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.42
PRKDC P78527 5/20 0.38
PIK3CD O00329 1/20 0.37
PIK3CB P42338 1/20 0.37
MAPT P10636 3/20 0.37
NPC1 O15118 2/20 0.37
ADK P55263 1/20 0.35
DRD4 P21917 1/20 0.34
GGPS1 O95749 1/20 0.34
ATM Q13315 1/20 0.34
KDM4E B2RXH2 2/20 0.34
ALDH1A1 P00352 2/20 0.34
GAA P10253 1/20 0.34
HPGD P15428 1/20 0.34
HSD17B10 Q99714 1/20 0.34
NCOA1 Q15788 1/20 0.33
HDAC8 Q9BY41 1/20 0.33
LMNA P02545 2/20 0.33
TSHR P16473 1/20 0.33
PRMT5 O14744 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21915075 0.93 ALOX5 (0.37) ALOX5PRKDCPIK3CDPIK3CBMAPT
SCHEMBL23439035 0.90 MAPT (0.45) MAPTNPC1ATMKDM4EALDH1A1
SCHEMBL9890187 0.89 NCOA1 (0.37) MAPTNPC1ATMKDM4EALDH1A1
SCHEMBL21147907 0.88 ALOX5 (0.50) ALOX5PRKDCPIK3CDPIK3CBMAPT
SCHEMBL30863907 0.88 NPC1 (0.40) MAPTNPC1ATMKDM4EALDH1A1
SCHEMBL15730368 0.88 NPC1 (0.40) MAPTNPC1ATMKDM4EALDH1A1
SCHEMBL18415392 0.87 ALOX5 (0.46) ALOX5PRKDCPIK3CDPIK3CBMAPT
SCHEMBL5028008 0.87 MAPT (0.33) MAPTNPC1DRD4ATMKDM4E
SCHEMBL21914467 0.87 ALOX5 (0.38) ALOX5PRKDCPIK3CDPIK3CBDRD4
SCHEMBL21914264 0.87 PRKDC (0.40) ALOX5PRKDCPIK3CDPIK3CBADK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200127214-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DEVICE HAVING THE SAME LG DISPLAY CO., LTD. (KR) 2020-04-23 US disclosed
US-20200119299-A1 ORGANIC LIGHT-EMITTING DIODE AND ORGANIC LIGHT-EMITTING DEVICE HAVING THE SAME LG DISPLAY CO., LTD (KR) 2020-04-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200127214-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DEVICE HAVING THE SAME MAP1LC3A, MAP1LC3C, MAP1LC3B ALOX5 197/4885PRKDC 3055/4885PIK3CD 2856/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.