SCHEMBL21914403

SCHEMBL21914403

c1ccc2c(c1)sc1c(-c3cccc4c3oc3ccc(-n5c6ccccc6c6cc(-n7c8ccccc8c8ccccc87)ccc65)cc34)cccc12

nearest known ligand 0.44

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PRKDC P78527 11/20 0.44
PIK3CD O00329 2/20 0.44
PIK3CB P42338 2/20 0.44
BRDT Q58F21 2/20 0.44
BRD4 O60885 1/20 0.44
PIK3CA P42336 1/20 0.44
MTOR P42345 1/20 0.44
PIK3CG P48736 1/20 0.44
KCNH2 Q12809 1/20 0.44
ALOX5 P09917 3/20 0.37
PARP14 Q460N5 1/20 0.35
ESR2 Q92731 2/20 0.32
ESR1 P03372 1/20 0.31
KDM4E B2RXH2 1/20 0.31
ATM Q13315 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
HTT P42858 1/20 0.30
PAX8 Q06710 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21914262 1.00 PRKDC (0.44) PRKDCPIK3CDPIK3CBBRDTBRD4
SCHEMBL21147912 0.98 PRKDC (0.45) PRKDCPIK3CDPIK3CBBRDTBRD4
SCHEMBL21915056 0.94 PRKDC (0.41) PRKDCPIK3CDPIK3CBBRDTBRD4
SCHEMBL23433203 0.94 PRKDC (0.45) PRKDCPIK3CDPIK3CBBRDTBRD4
SCHEMBL21914406 0.93 PRKDC (0.41) PRKDCPIK3CDPIK3CBBRDTBRD4
SCHEMBL21915050 0.93 PRKDC (0.39) PRKDCPIK3CDPIK3CBBRDTBRD4
SCHEMBL21915055 0.93 PRKDC (0.41) PRKDCPIK3CDPIK3CBBRDTBRD4
SCHEMBL21914269 0.93 PRKDC (0.41) PRKDCPIK3CDPIK3CBBRDTBRD4
SCHEMBL21914408 0.93 PRKDC (0.41) PRKDCPIK3CDPIK3CBBRDTBRD4
SCHEMBL21914706 0.92 PRKDC (0.40) PRKDCPIK3CDPIK3CBBRDTBRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11588113-B2 Organic light emitting diode and organic light emitting device having the same LG DISPLAY CO., LTD. (KR) 2023-02-21 US disclosed
US-20200136059-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DEVICE HAVING THE SAME LG DISPLAY CO., LTD. (KR) 2020-04-30 US disclosed
US-20200127214-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DEVICE HAVING THE SAME LG DISPLAY CO., LTD. (KR) 2020-04-23 US disclosed
US-20200119299-A1 ORGANIC LIGHT-EMITTING DIODE AND ORGANIC LIGHT-EMITTING DEVICE HAVING THE SAME LG DISPLAY CO., LTD (KR) 2020-04-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200127214-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DEVICE HAVING THE SAME MAP1LC3A, MAP1LC3C, MAP1LC3B PRKDC 3055/4885PIK3CD 2856/4885PIK3CB 3862/4885
US-20200136059-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DEVICE HAVING THE SAME OCIAD1, OCIAD2, APOL1 PRKDC 2937/4885PIK3CD 1678/4885PIK3CB 3068/4885
US-11588113-B2 Organic light emitting diode and organic light emitting device having the same OCIAD1, OCIAD2, APOL1 PRKDC 2937/4885PIK3CD 1678/4885PIK3CB 3068/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.