SCHEMBL21914643

SCHEMBL21914643

O=S(=O)(Nc1ccccc1)c1cccc2c(S(=O)(=O)Nc3ccccc3)cccc12

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.61
PGR P06401 1/20 0.61
CCR8 P51685 1/20 0.58
IL1RN P18510 1/20 0.57
KEAP1 Q14145 1/20 0.57
ERAP1 Q9NZ08 1/20 0.57
DUSP3 P51452 1/20 0.54
PTPN5 P54829 1/20 0.54
CASP6 P55212 1/20 0.54
PTPN11 Q06124 1/20 0.54
CTDSP1 Q9GZU7 1/20 0.54
EDNRA P25101 2/20 0.54
KDM4E B2RXH2 1/20 0.54
FABP4 P15090 3/20 0.54
WDR5 P61964 1/20 0.54
FABP5 Q01469 1/20 0.54
MEN1 O00255 3/20 0.53
ALDH1A1 P00352 3/20 0.53
KMT2A Q03164 3/20 0.53
PKM P14618 2/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL812673 0.90 TSHR (0.74) TSHRPGRIL1RNKEAP1ERAP1
SCHEMBL31110643 0.90 TSHR (0.74) TSHRPGRIL1RNKEAP1ERAP1
SCHEMBL4488183 0.89 TSHR (0.60) TSHRPGRCCR8EDNRAKDM4E
Hydrochloric Acid SCHEMBL4450885 0.88 NSD2 (0.62) TSHRPGRCCR8EDNRA
SCHEMBL7627388 0.87 KEAP1 (0.67) TSHRPGRIL1RNKEAP1ERAP1
SCHEMBL9137231 0.85 EDNRA (0.77) TSHREDNRAKDM4E
SCHEMBL9478942 0.84 TSHR (0.71) TSHRPGRPTPN5MEN1ALDH1A1
SCHEMBL9137240 0.83 CCR8 (0.55) TSHRPGRCCR8IL1RNKEAP1
SCHEMBL19297161 0.83 MEN1 (0.71) TSHRPGRCCR8IL1RNKEAP1
SCHEMBL3617602 0.83 TET2 (0.57) CCR8IL1RNKEAP1ERAP1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11656384-B2 Composition, film, lens, solid state imaging element, and compounds FUJIFILM CORPORATION (JP) 2023-05-23 US disclosed
US-11656384-B2 Composition, film, lens, solid state imaging element, and compounds FUJIFILM CORPORATION (JP) 2023-05-23 US disclosed
US-20200116896-A1 COMPOSITION, FILM, LENS, SOLID STATE IMAGING ELEMENT, AND COMPOUNDS FUJIFILM CORPORATION (JP) 2020-04-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11656384-B2 Composition, film, lens, solid state imaging element, and compounds UACA, F12, ERGIC1 TSHR 4112/4885PGR 3292/4885CCR8 2435/4885
US-20200116896-A1 COMPOSITION, FILM, LENS, SOLID STATE IMAGING ELEMENT, AND COMPOUNDS UACA, F12, ERGIC1 TSHR 4112/4885PGR 3292/4885CCR8 2435/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.