SCHEMBL812673

SCHEMBL812673

O=S(=O)(Nc1ccccc1)c1cccc2ccccc12

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.74
PGR P06401 1/20 0.74
RORA P35398 1/20 0.62
RORC P51449 1/20 0.62
NR1H2 P55055 1/20 0.62
NR1H4 Q96RI1 1/20 0.62
ALDH1A1 P00352 2/20 0.61
HTT P42858 1/20 0.61
PFKFB3 Q16875 1/20 0.61
HDAC1 Q13547 1/20 0.59
HCRTR1 O43613 1/20 0.59
TYMS P04818 1/20 0.56
MAPT P10636 2/20 0.55
MEN1 O00255 1/20 0.55
KMT2A Q03164 1/20 0.55
PTPN2 P17706 1/20 0.54
PTPN1 P18031 1/20 0.54
PTPN5 P54829 1/20 0.54
ACLY P53396 1/20 0.54
GHSR Q92847 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31110643 1.00 TSHR (0.74) TSHRPGRRORARORCNR1H2
SCHEMBL9478942 0.93 TSHR (0.71) TSHRPGRRORARORCNR1H2
SCHEMBL21914643 0.90 TSHR (0.61) TSHRPGRRORARORCNR1H2
SCHEMBL5046687 0.88 TSHR (0.64) TSHRPGRRORARORCNR1H2
SCHEMBL16785737 0.86 TSHR (0.67) TSHRPGRRORARORCNR1H2
SCHEMBL6409546 0.86 TSHR (0.67) TSHRPGRRORARORCNR1H2
SCHEMBL3261087 0.86 TSHR (0.71) TSHRPGRRORARORCNR1H2
SCHEMBL9480187 0.86 ALDH1A1 (0.62) TSHRPGRRORARORCNR1H2
SCHEMBL15762086 0.86 TSHR (1.00) TSHRPGRRORARORCNR1H2
SCHEMBL9481100 0.85 TSHR (0.64) TSHRPGRRORARORCNR1H2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 189 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119753771-A Electroless copper plating solution and preparation method thereof 河源金晟新电子材料有限公司 2025-04-04 CN claimed
US-20230288610-A1 WAVELENGTH SELECTIVE ABSORPTION FILTER AND DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2023-09-14 US disclosed
US-20190382422-A1 SALICYLIC ACID DERIVATIVES, PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, COMPOSITION THEREOF AND METHOD OF USE THEREOF THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) 2019-12-19 US disclosed
US-10377780-B2 Salicylic acid derivatives, pharmaceutically acceptable salt thereof, composition thereof and method of use thereof THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) 2019-08-13 US disclosed
US-20170267704-A1 SALICYLIC ACID DERIVATIVES, PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, COMPOSITION THEREOF AND METHOD OF USE THEREOF THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) 2017-09-21 US disclosed
US-9726932-B2 Optical film, optical compensation film, polarizing plate and liquid crystal display FUJIFILM CORPORATION (JP) 2017-08-08 US disclosed
US-9726932-B2 Optical film, optical compensation film, polarizing plate and liquid crystal display FUJIFILM CORPORATION (JP) 2017-08-08 US disclosed
US-9650399-B2 Salicylic acid derivatives, pharmaceutically acceptable salt thereof, composition thereof and method of use thereof THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) 2017-05-16 US disclosed
US-9563075-B2 Method for manufacturing liquid crystal display device provided with front plate, and liquid crystal display device provided with front plate Konica Minolta, Inc. (JP) 2017-02-07 US disclosed
US-9563075-B2 Method for manufacturing liquid crystal display device provided with front plate, and liquid crystal display device provided with front plate Konica Minolta, Inc. (JP) 2017-02-07 US disclosed
US-20070092663-A1 Cellulose ester film, polarizing plate and display KONICA MINOLTA OPTO, INC. 2007-04-26 US disclosed
US-20070076155-A1 Optical film, optical compensation film, polarizing plate and liquid crystal display FUJI PHOTO FILM CO., LTD. (JP) 2007-04-05 US disclosed
US-20070076155-A1 Optical film, optical compensation film, polarizing plate and liquid crystal display FUJI PHOTO FILM CO., LTD. (JP) 2007-04-05 US disclosed
US-20070059458-A1 Cellulose acylate film, optically compensatory film, polarizing plate and liquid crystal display FUJI PHOTO FILM CO., LTD. (JP) 2007-03-15 US disclosed
US-20070059458-A1 Cellulose acylate film, optically compensatory film, polarizing plate and liquid crystal display FUJI PHOTO FILM CO., LTD. (JP) 2007-03-15 US disclosed
US-4918183-A Monoazo dyes, process for their preparation, and the use thereof CIBA-GEIGY CORPORATION (US) 1990-04-17 US disclosed
EP-0082383-B1 PROCESS FOR PREPARING POLYCARBONATES CONTAINING SULFONE ANILIDE END GROUPS BAYER AG (DE) 1985-08-28 EP disclosed
US-4471104-A SELF EXTINGUISHING BAYER AKTIENGESELLSCHAFT (DE) 1984-09-11 US disclosed
US-4464452-A NEGATIVE CHARGE ENHANCER XEROX CORPORATION (US) 1984-08-07 US disclosed
EP-0082383-A1 Process for preparing polycarbonates containing sulfone anilide end groups BAYER AG (DE) 1983-06-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190382422-A1 SALICYLIC ACID DERIVATIVES, PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, COMPOSITION THEREOF AND METHOD OF USE THEREOF STAT3, STAT5A, STAT6 TSHR 3326/4885PGR 2419/4885RORA 224/4885
US-20170267704-A1 SALICYLIC ACID DERIVATIVES, PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, COMPOSITION THEREOF AND METHOD OF USE THEREOF STAT3, STAT5A, STAT6 TSHR 3326/4885PGR 2419/4885RORA 224/4885
US-10377780-B2 Salicylic acid derivatives, pharmaceutically acceptable salt thereof, composition thereof and method of use thereof STAT3, STAT5A, STAT6 TSHR 3326/4885PGR 2419/4885RORA 224/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.