Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.33 |
| ▸ | MYLK | Q15746 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | PRKCG | P05129 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PRKCA | P17252 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 2/20 | 0.33 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | CSF1R | P07333 | 1/20 | 0.31 |
| ▸ | KIT | P10721 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2115975 | 0.81 | LMNA (0.43) | LMNAALDH1A1PRKCEMYLKTDP1 | |
| SCHEMBL25503495 | 0.81 | CYP2C9 (0.43) | LMNAADRA1AALDH1A1PRKCEMYLK | |
| SCHEMBL19859254 | 0.81 | LMNA (0.36) | LMNAADRA1AALDH1A1PRKCEMYLK | |
| SCHEMBL2123145 | 0.81 | LMNA (0.47) | LMNAADRA1AALDH1A1MEN1KMT2A | |
| SCHEMBL2122317 | 0.81 | ADRA1A (0.37) | LMNAADRA1AALDH1A1PRKCEMYLK | |
| SCHEMBL19859242 | 0.79 | AGBL2 (0.40) | LMNAADRA1AALDH1A1PRKCEMYLK | |
| SCHEMBL21914765 | 0.77 | AGBL2 (0.39) | AGBL2 | |
| SCHEMBL19859150 | 0.74 | KDM4E (0.40) | LMNAALDH1A1PRKCEMAPTAPEX1 | |
| SCHEMBL21326635 | 0.73 | AGBL2 (0.41) | LMNAALDH1A1TDP1MAPTAGBL2 | |
| SCHEMBL25272117 | 0.72 | AGBL2 (0.32) | AGBL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3640253-A1 | 6H-THIENO[2,3-E][1,2,4]TRIAZOLO[3,4-C][1,2,4]TRIAZEPINE DERIVATIVE | AYUMI Pharmaceutical Corporation (JP) | 2020-04-22 | — | — | EP | disclosed |