Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 10/20 | 0.71 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.71 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.53 |
| ▸ | USP2 | O75604 | 2/20 | 0.53 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.53 |
| ▸ | MTOR | P42345 | 4/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | CASP7 | P55210 | 1/20 | 0.49 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3727348 | 0.85 | PIK3CA (0.60) | PIK3CAPIK3CDAOC3HSD17B10ALDH1A1 | |
| SCHEMBL2369411 | 0.85 | PIK3CA (0.60) | PIK3CAPIK3CDAOC3HSD17B10ALDH1A1 | |
| SCHEMBL5172881 | 0.83 | PIK3CA (1.00) | PIK3CAPIK3CDPIK3CGMTORHTT | |
| SCHEMBL2369996 | 0.79 | PIK3CA (0.71) | PIK3CAPIK3CDAOC3PIK3CGMTOR | |
| SCHEMBL3730124 | 0.79 | PIK3CA (0.77) | PIK3CAPIK3CDPIK3CGMTORMAPT | |
| SCHEMBL3721523 | 0.78 | PIK3CA (0.75) | PIK3CAPIK3CDPIK3CGMTORPIK3CB | |
| SCHEMBL2369790 | 0.78 | PIK3CA (0.78) | PIK3CAPIK3CDPIK3CGMTOR | |
| SCHEMBL3722243 | 0.76 | PIK3CA (0.72) | PIK3CAPIK3CDCYP1A2CYP2C19PIK3CG | |
| SCHEMBL3718879 | 0.76 | PIK3CA (0.55) | PIK3CAPIK3CDAOC3HSD17B10ALDH1A1 | |
| SCHEMBL1309370 | 0.75 | PIK3CA (0.71) | PIK3CAPIK3CDPIK3CGMTORPIK3R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3626699-A1 | SSAO INHIBITOR | Shandong Danhong Pharmaceutical Co., Ltd. (CN) | 2020-03-25 | — | — | EP | disclosed |