Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE6D | O43924 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.34 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21915542 | 0.86 | PDE6D (0.39) | PDE6DKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL21915710 | 0.85 | MAPT (0.47) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL17640569 | 0.80 | CYP19A1 (0.51) | PDE6DKDM4EHSD17B10MAPTSMN1; SMN2 | |
| SCHEMBL17640556 | 0.79 | CYP19A1 (0.50) | PDE6DKDM4EHSD17B10MAPTSMN1; SMN2 | |
| SCHEMBL17640631 | 0.79 | CYP19A1 (0.50) | PDE6DKDM4EHSD17B10MAPTSMN1; SMN2 | |
| SCHEMBL21915703 | 0.79 | DHFR (0.39) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL21915555 | 0.78 | PDE6D (0.37) | PDE6DMAPTHSD17B1HSD17B2CYP19A1 | |
| SCHEMBL21915469 | 0.78 | HSD17B1 (0.43) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL21915388 | 0.78 | HSD17B1 (0.38) | PDE6DKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL21915386 | 0.77 | MAPT (0.35) | PDE6DKDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020062375-A1 | 1,2,4-THIADIAZOLE COMPOUNDS AND PREPARATION METHOD THEREFOR AND USE THEREOF | 武汉尚赛光电科技有限公司 | 2020-04-02 | — | — | WO | disclosed |