Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.36 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.34 |
| ▸ | FURIN | P09958 | 4/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.32 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.32 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.32 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.31 |
| ▸ | TLR2 | O60603 | 2/20 | 0.31 |
| ▸ | RRM1 | P23921 | 1/20 | 0.30 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.30 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21915070 | 0.85 | SIRT6 (0.41) | SIRT6SIRT1SMN1; SMN2DPP7FURIN | |
| SCHEMBL25070732 | 0.83 | SIRT6 (0.41) | SIRT6SIRT1SMN1; SMN2DPP7FURIN | |
| SCHEMBL21914973 | 0.81 | SMN1; SMN2 (0.33) | SIRT6SIRT1SMN1; SMN2FURINCTSL | |
| SCHEMBL24703694 | 0.79 | SMN1; SMN2 (0.32) | SIRT6SIRT1SMN1; SMN2FURINSIRT5 | |
| SCHEMBL22692385 | 0.77 | SIRT6 (0.38) | SIRT6SIRT1SMN1; SMN2FURINPRSS1 | |
| SCHEMBL24172987 | 0.76 | FURIN (0.33) | SMN1; SMN2DPP7FURINNOD1SIRT5 | |
| SCHEMBL21152822 | 0.76 | SIRT6 (0.44) | SIRT6SIRT1SMN1; SMN2DPP7FURIN | |
| SCHEMBL24173258 | 0.76 | C3AR1 (0.34) | SIRT6SIRT1SMN1; SMN2FURINSIRT5 | |
| SCHEMBL20803561 | 0.76 | C3AR1 (0.34) | SIRT6SIRT1SMN1; SMN2FURINSIRT5 | |
| SCHEMBL21914903 | 0.76 | C3AR1 (0.34) | SIRT6SIRT1SMN1; SMN2FURINSIRT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10624968-B2 | Compounds for treating cancer | Bicyclerd Limited (GB) | 2020-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10624968-B2 | Compounds for treating cancer | TP53, VHL, MYC | SIRT6 1621/4885SIRT1 1018/4885SMN1; SMN2 3956/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.