Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | FURIN | P09958 | 5/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.38 |
| ▸ | RRM1 | P23921 | 1/20 | 0.38 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.36 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.36 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.36 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | TLR2 | O60603 | 2/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25070732 | 0.95 | SIRT6 (0.41) | SIRT6SIRT1SMN1; SMN2FURINDPP7 | |
| SCHEMBL21152822 | 0.89 | SIRT6 (0.44) | SIRT6SIRT1SMN1; SMN2FURINDPP7 | |
| SCHEMBL24173260 | 0.85 | FURIN (0.47) | SIRT6SIRT1SMN1; SMN2FURINDPP7 | |
| SCHEMBL21915906 | 0.85 | SIRT6 (0.36) | SIRT6SIRT1SMN1; SMN2FURINDPP7 | |
| SCHEMBL22702596 | 0.80 | CTSL (0.47) | SIRT6SIRT1FURINPRSS1NOD1 | |
| SCHEMBL24015397 | 0.79 | FURIN (0.36) | SIRT6SIRT1SMN1; SMN2FURINDPP7 | |
| SCHEMBL19101872 | 0.79 | FURIN (0.36) | SIRT6SIRT1SMN1; SMN2FURINDPP7 | |
| SCHEMBL20385879 | 0.79 | SMN1; SMN2 (0.39) | SIRT6SIRT1SMN1; SMN2FURINDPP7 | |
| SCHEMBL18818915 | 0.79 | REN (0.34) | SIRT6SIRT1SMN1; SMN2FURIN | |
| SCHEMBL19765297 | 0.78 | SIRT6 (0.38) | SIRT6SIRT1SMN1; SMN2FURINDPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10624968-B2 | Compounds for treating cancer | Bicyclerd Limited (GB) | 2020-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10624968-B2 | Compounds for treating cancer | TP53, VHL, MYC | SIRT6 1621/4885SIRT1 1018/4885SMN1; SMN2 3956/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.