Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP8 | Q6V1X1 | 5/20 | 0.47 |
| ▸ | DPP9 | Q86TI2 | 5/20 | 0.47 |
| ▸ | DPP7 | Q9UHL4 | 5/20 | 0.47 |
| ▸ | GSR | P00390 | 1/20 | 0.44 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.43 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.43 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 2/20 | 0.41 |
| ▸ | CPB2 | Q96IY4 | 3/20 | 0.40 |
| ▸ | MMP2 | P08253 | 2/20 | 0.38 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.36 |
| ▸ | TERT | O14746 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28069698 | 0.95 | DPP7 (0.46) | DPP8DPP9DPP7GSRGNAI3 | |
| SCHEMBL2183058 | 0.89 | DPP8 (0.42) | DPP8DPP9DPP7GSRGNAI3 | |
| SCHEMBL7751944 | 0.89 | DPP7 (0.50) | DPP8DPP9DPP7GSRGNAI3 | |
| SCHEMBL7751947 | 0.89 | DPP7 (0.50) | DPP8DPP9DPP7GSRGNAI3 | |
| SCHEMBL8495681 | 0.83 | DPP7 (0.56) | DPP8DPP9DPP7GSRGNAI3 | |
| SCHEMBL2183995 | 0.82 | NPY4R (0.46) | DPP8DPP9DPP7GNAI3GNAO1 | |
| SCHEMBL1651538 | 0.82 | DPP8 (0.48) | DPP8DPP9DPP7GSRGNAI3 | |
| SCHEMBL2192330 | 0.82 | DPP8 (0.45) | DPP8DPP9DPP7GSRGNAI3 | |
| SCHEMBL8567236 | 0.82 | FOLH1 (0.47) | DPP8DPP9DPP7GSRGNAI3 | |
| SCHEMBL1888867 | 0.82 | FOLH1 (0.47) | DPP8DPP9DPP7GSRGNAI3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190070251-A1 | POLYMER CONJUGATES OF THERAPEUTIC PEPTIDES | NEKTAR THERAPEUTICS | 2019-03-07 | — | — | US | disclosed |
| US-9682153-B2 | Polymer conjugates of therapeutic peptides | NEKTAR THERAPEUTICS (US) | 2017-06-20 | — | — | US | disclosed |
| US-20160022828-A1 | POLYMER CONJUGATES OF THERAPEUTIC PEPTIDES | NEKTAR THERAPEUTICS | 2016-01-28 | — | — | US | disclosed |
| US-20110171312-A1 | MODIFIED THERAPEUTIC PEPTIDES, METHODS OF THEIR PREPARATION AND USE | NEKTAR THERAPEUTICS (US) | 2011-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160022828-A1 | POLYMER CONJUGATES OF THERAPEUTIC PEPTIDES | NGLY1, CD44, IAPP | DPP8 644/4885DPP9 996/4885DPP7 450/4885 |
| US-20190070251-A1 | POLYMER CONJUGATES OF THERAPEUTIC PEPTIDES | NGLY1, CD44, IAPP | DPP8 644/4885DPP9 996/4885DPP7 450/4885 |
| US-20110171312-A1 | MODIFIED THERAPEUTIC PEPTIDES, METHODS OF THEIR PREPARATION AND USE | DNPEP, VIP, PTMS | DPP8 590/4885DPP9 903/4885DPP7 594/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.