Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HKDC1 | Q2TB90 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CDC25A | P30304 | 2/20 | 0.34 |
| ▸ | CDC25B | P30305 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.34 |
| ▸ | GMNN | O75496 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL235760 | 0.76 | KDM4E (0.40) | KDM4ECYP3A4MAPTMEN1KMT2A | |
| SCHEMBL14949882 | 0.69 | — | — | |
| SCHEMBL9056800 | 0.64 | KDM4E (0.33) | HKDC1KDM4ETP53CYP3A4MAPT | |
| SCHEMBL6053930 | 0.62 | ERBB2 (0.43) | HKDC1KDM4ETP53CYP3A4MAPT | |
| SCHEMBL5318359 | 0.62 | — | — | |
| SCHEMBL21723179 | 0.62 | ERBB2 (0.48) | HKDC1KDM4ETP53CYP3A4MAPT | |
| SCHEMBL16057083 | 0.60 | HKDC1 (0.44) | HKDC1KDM4ETP53CYP3A4MAPT | |
| SCHEMBL14829815 | 0.60 | HKDC1 (0.39) | HKDC1KDM4ETP53CYP3A4MAPT | |
| SCHEMBL1960919 | 0.60 | HKDC1 (0.54) | HKDC1KDM4ETP53CYP3A4MAPT | |
| SCHEMBL9175352 | 0.60 | MAPT (0.42) | HKDC1KDM4ETP53CYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110173718-A1 | HERBICIDE TOLERANT PLANTS | SYNGENTA CROP PROTECTION, INC. (US) | 2011-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110173718-A1 | HERBICIDE TOLERANT PLANTS | HPD, LCT, GNPAT | HKDC1 134/4885KDM4E 3252/4885TP53 2276/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.