SCHEMBL21924973

SCHEMBL21924973

C=CC(=O)Nc1ccc(C#N)c(C(F)(F)F)c1

nearest known ligand 0.57

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TGM2 P21980 1/20 0.54
AR P10275 9/20 0.53
TAS2R14 Q9NYV8 1/20 0.52
BLM P54132 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL324379 0.84 AR (0.56) ARTAS2R14BLM
SCHEMBL17658051 0.84 BLM (0.63) ARTAS2R14BLM
SCHEMBL3181581 0.84 ALDH1A1 (0.54) ARTAS2R14
SCHEMBL28904279 0.84 AR (0.51) ARTAS2R14BLM
SCHEMBL13481381 0.84 ALDH1A1 (0.54) ARTAS2R14
SCHEMBL3181575 0.84 ALDH1A1 (0.54) ARTAS2R14
SCHEMBL26364955 0.84 AR (0.51) ARTAS2R14
SCHEMBL2132359 0.83 AR (0.53) AR
SCHEMBL5247689 0.82 TAS2R14 (0.60) ARTAS2R14BLM
SCHEMBL30104708 0.82 AR (0.49) ARTAS2R14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120193362-A Breathable sports bandage and preparation method thereof 江苏仪征康普诺医疗器械有限公司 2025-06-24 CN disclosed
US-12044968-B2 Protective film-forming composition having acetal structure and amide structure NISSAN CHEMICAL CORPORATION (JP) 2024-07-23 US disclosed
US-12044968-B2 Protective film-forming composition having acetal structure and amide structure NISSAN CHEMICAL CORPORATION (JP) 2024-07-23 US disclosed
US-11982941-B2 Flexographic printing plate precursor SUMITOMO RIKO COMPANY LIMITED (JP) 2024-05-14 US disclosed
US-20230303496-A1 SELECTIVE ANDROGEN RECEPTOR COVALENT ANTAGONISTS (SARCAs) AND METHODS OF USE THEREOF UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION 2023-09-28 US disclosed
EP-3650239-B1 FLEXOGRAPHIC PRINTING PLATE PRECURSOR SUMITOMO RIKO CO LTD (JP) 2023-04-19 EP disclosed
US-20220026806-A1 PROTECTIVE FILM-FORMING COMPOSITION HAVING ACETAL STRUCTURE AND AMIDE STRUCTURE NISSAN CHEMICAL CORPORATION (JP) 2022-01-27 US disclosed
CN-111372787-B Flexographic printing plate precursor 住友理工株式会社 2021-12-21 CN disclosed
US-20200241416-A1 FLEXOGRAPHIC PRINTING PLATE PRECURSOR SUMITOMO RIKO COMPANY LIMITED (JP) 2020-07-30 US disclosed
CN-111372787-A Flexographic printing plate precursor 住友理工株式会社 2020-07-03 CN disclosed
EP-3650239-A1 FLEXOGRAPHIC PRINTING PLATE PRECURSOR Sumitomo Riko Company Limited (JP) 2020-05-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230303496-A1 SELECTIVE ANDROGEN RECEPTOR COVALENT ANTAGONISTS (SARCAs) AND METHODS OF USE THEREOF AR, BRCA1, PSMA1 TGM2 2655/4885AR 1/4885TAS2R14 4096/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.