Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 2/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.30 |
| ▸ | FEN1 | P39748 | 1/20 | 0.30 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16389671 | 0.88 | PTGS2 (0.35) | PTGS2PTGS1 | |
| SCHEMBL17018436 | 0.86 | POLB (0.35) | S1PR1POLBAGBL2 | |
| SCHEMBL21925095 | 0.84 | POLB (0.33) | S1PR1POLBAGBL2 | |
| SCHEMBL17342181 | 0.80 | POLB (0.41) | S1PR1POLB | |
| SCHEMBL17008988 | 0.79 | RAB9A (0.43) | POLB | |
| SCHEMBL21925093 | 0.79 | RAB9A (0.32) | POLB | |
| SCHEMBL19366944 | 0.79 | KCNH2 (0.35) | PTGS2POLBPTGS1FEN1 | |
| SCHEMBL29431655 | 0.78 | POLB (0.40) | S1PR1POLB | |
| SCHEMBL15929737 | 0.78 | POLB (0.40) | S1PR1POLB | |
| SCHEMBL18624698 | 0.78 | PDE2A (0.35) | PTGS2POLBPTGS1FEN1AGBL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3016949-B1 | PESTICIDALLY ACTIVE BI- OR TRICYCLIC HETEROCYCLES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2020-05-13 | — | — | EP | claimed |
| EP-3016949-B1 | PESTICIDALLY ACTIVE BI- OR TRICYCLIC HETEROCYCLES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2020-05-13 | — | — | EP | disclosed |