Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | QRFPR | Q96P65 | 1/20 | 0.30 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.30 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | RORC | P51449 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21925124 | 0.83 | KDM4E (0.37) | CYP2C9ALDH1A1LMNAKDM4EMEN1 | |
| SCHEMBL17514086 | 0.82 | ALDH1A1 (0.34) | ALDH1A1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL30958301 | 0.82 | ALDH1A1 (0.34) | ALDH1A1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL16803688 | 0.81 | POLB (0.37) | ALDH1A1LMNAGAAMAPTMEN1 | |
| SCHEMBL24313893 | 0.81 | AGPAT2 (0.32) | AGPAT2POLB | |
| SCHEMBL16612304 | 0.81 | POLB (0.48) | ALDH1A1LMNAKDM4EGAAMAPT | |
| SCHEMBL17832751 | 0.81 | ALDH1A1 (0.35) | CYP2C9ALDH1A1LMNAKDM4EGAA | |
| SCHEMBL18819764 | 0.81 | ALDH1A1 (0.35) | CYP2C9ALDH1A1LMNAKDM4EGAA | |
| SCHEMBL17432151 | 0.80 | JAK2 (0.34) | ALDH1A1LMNAKDM4EGAAMAPT | |
| SCHEMBL30958296 | 0.80 | CA12 (0.33) | CYP2C9ALDH1A1KDM4EGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3778598-A2 | PESTICIDALLY ACTIVE BI- OR TRICYCLIC HETEROCYCLES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2021-02-17 | — | — | EP | disclosed |
| EP-3778599-A2 | PESTICIDALLY ACTIVE BI- OR TRICYCLIC HETEROCYCLES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2021-02-17 | — | — | EP | disclosed |
| EP-3016949-B1 | PESTICIDALLY ACTIVE BI- OR TRICYCLIC HETEROCYCLES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2020-05-13 | — | — | EP | disclosed |