Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | DHODH | Q02127 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | GSR | P00390 | 2/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 3/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17832804 | 0.85 | ALDH1A1 (0.34) | ALDH1A1DHODHPKMGSROPRM1 | |
| SCHEMBL18819688 | 0.81 | MEN1 (0.39) | DHODHPKMGSROPRM1MEN1 | |
| SCHEMBL24286105 | 0.81 | PTGS2 (0.34) | ALDH1A1DHODHPKMNPC1RAB9A | |
| SCHEMBL21925161 | 0.81 | CYP2C9 (0.33) | ALDH1A1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL18819854 | 0.81 | ALDH1A1 (0.33) | ALDH1A1DHODHPKMNPC1RAB9A | |
| SCHEMBL18819759 | 0.80 | NPC1 (0.37) | DHODHGSROPRM1NPC1RAB9A | |
| SCHEMBL18131807 | 0.79 | HSD17B10 (0.33) | ALDH1A1PKMNPC1RAB9AMEN1 | |
| SCHEMBL19993432 | 0.79 | ALDH1A1 (0.32) | ALDH1A1PKMMAPTLMNA | |
| SCHEMBL17967734 | 0.79 | DDR1 (0.31) | ALDH1A1 | |
| SCHEMBL17832751 | 0.79 | ALDH1A1 (0.35) | ALDH1A1PKMNPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10550116-B2 | Fused bicyclic heterocycle derivatives as pesticides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-02-04 | — | — | US | disclosed |
| US-10550116-B2 | Fused bicyclic heterocycle derivatives as pesticides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-02-04 | — | — | US | disclosed |
| US-20180305353-A1 | FUSED BICYCLIC HETEROCYCLE DERIVATIVES AS PESTICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-10-25 | — | — | US | disclosed |
| WO-2017072039-A1 | CONDENSED BICYCLIC HETEROCYCLE DERIVATIVES AS PEST CONTROL AGENTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-05-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180305353-A1 | FUSED BICYCLIC HETEROCYCLE DERIVATIVES AS PESTICIDES | DDT, BCHE, ACHE | ALDH1A1 468/4885DHODH 1011/4885PKM 2278/4885 |
| US-10550116-B2 | Fused bicyclic heterocycle derivatives as pesticides | DDT, BCHE, ACHE | ALDH1A1 468/4885DHODH 1011/4885PKM 2278/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.