Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 4/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 14/20 | 0.69 |
| ▸ | MEN1 | O00255 | 13/20 | 0.69 |
| ▸ | MAPT | P10636 | 9/20 | 0.69 |
| ▸ | LMNA | P02545 | 7/20 | 0.69 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.69 |
| ▸ | THRB | P10828 | 1/20 | 0.69 |
| ▸ | POLB | P06746 | 2/20 | 0.68 |
| ▸ | GAA | P10253 | 1/20 | 0.67 |
| ▸ | RAB9A | P51151 | 4/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | NPC1 | O15118 | 3/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.58 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21925171 | 1.00 | PIM1 (0.70) | PIM1KMT2AMEN1MAPTLMNA | |
| SCHEMBL26500547 | 0.80 | AGTR1 (0.61) | PIM1KMT2AMEN1MAPTPOLB | |
| SCHEMBL26500741 | 0.79 | AGTR1 (0.60) | PIM1KMT2AMEN1MAPTPOLB | |
| SCHEMBL12281247 | 0.75 | KMT2A (0.69) | KMT2AMEN1MAPTLMNANPSR1 | |
| SCHEMBL9156121 | 0.74 | AGTR1 (1.00) | KMT2AMEN1POLBRAB9ANPC1 | |
| SCHEMBL2834478 | 0.74 | PIM1 (0.69) | PIM1KMT2AMEN1MAPTLMNA | |
| SCHEMBL2834480 | 0.74 | PIM1 (0.69) | PIM1KMT2AMEN1MAPTLMNA | |
| SCHEMBL14115818 | 0.73 | PIM1 (1.00) | PIM1KMT2AMEN1MAPTGAA | |
| SCHEMBL29696924 | 0.73 | PIM1 (1.00) | PIM1KMT2AMEN1MAPTGAA | |
| SCHEMBL4934423 | 0.73 | PIM1 (1.00) | PIM1KMT2AMEN1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12306164-B2 | Therapeutic drug for lipid-peroxidation-induced diseases and screening method for therapeutic drugs for lipid-peroxidation-induced diseases | Yamamada, Ken-Ichi (JP) | 2025-05-20 | — | — | US | disclosed |
| CN-119510740-A | Therapeutic agent for lipid peroxidation-induced disease and screening method therefor | 扶桑药品工业株式会社 | 2025-02-25 | — | — | CN | disclosed |
| US-20230324358-A1 | THERAPEUTIC DRUG FOR LIPID-PEROXIDATION-INDUCED DISEASES AND SCREENING METHOD FOR THERAPEUTIC DRUGS FOR LIPID-PEROXIDATION-INDUCED DISEASES | FUSO PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 2023-10-12 | — | — | US | disclosed |
| US-20230324359-A1 | THERAPEUTIC DRUG FOR LIPID-PEROXIDATION-INDUCED DISEASES AND SCREENING METHOD FOR THERAPEUTIC DRUGS FOR LIPID-PEROXIDATION-INDUCED DISEASES | FUSO PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 2023-10-12 | — | — | US | disclosed |
| US-11519893-B2 | Therapeutic drug for lipid-peroxidation-induced diseases and screening method for therapeutic drugs for lipid-peroxidation-induced diseases | YAMADA, Ken-ichi (JP) | 2022-12-06 | — | — | US | disclosed |
| US-20200158709-A1 | THERAPEUTIC DRUG FOR LIPID-PEROXIDATION-INDUCED DISEASES AND SCREENING METHOD FOR THERAPEUTIC DRUGS FOR LIPID-PEROXIDATION-INDUCED DISEASES | FUSO PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 2020-05-21 | — | — | US | disclosed |
| EP-3650860-A1 | THERAPEUTIC DRUG FOR LIPID-PEROXIDATION-INDUCED DISEASES AND SCREENING METHOD FOR THERAPEUTIC DRUGS FOR LIPID-PEROXIDATION-INDUCED DISEASES | Yamada, Ken-Ichi (JP) | 2020-05-13 | — | — | EP | disclosed |
| CN-111033257-A | Therapeutic agent for lipid peroxidation-induced disease and method for screening same | 扶桑药品工业株式会社 | 2020-04-17 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11519893-B2 | Therapeutic drug for lipid-peroxidation-induced diseases and screening method for therapeutic drugs for lipid-peroxidation-induced diseases | GPX4, GPX1, ALOX15 | PIM1 2199/4885KMT2A 4337/4885MEN1 4562/4885 |
| US-20200158709-A1 | THERAPEUTIC DRUG FOR LIPID-PEROXIDATION-INDUCED DISEASES AND SCREENING METHOD FOR THERAPEUTIC DRUGS FOR LIPID-PEROXIDATION-INDUCED DISEASES | GPX4, GPX1, ALOX15 | PIM1 2199/4885KMT2A 4337/4885MEN1 4562/4885 |
| US-12306164-B2 | Therapeutic drug for lipid-peroxidation-induced diseases and screening method for therapeutic drugs for lipid-peroxidation-induced diseases | GPX4, GPX1, ALOX15 | PIM1 2199/4885KMT2A 4337/4885MEN1 4562/4885 |
| US-20230324358-A1 | THERAPEUTIC DRUG FOR LIPID-PEROXIDATION-INDUCED DISEASES AND SCREENING METHOD FOR THERAPEUTIC DRUGS FOR LIPID-PEROXIDATION-INDUCED DISEASES | GPX4, GPX1, ALOX15 | PIM1 2199/4885KMT2A 4337/4885MEN1 4562/4885 |
| US-20230324359-A1 | THERAPEUTIC DRUG FOR LIPID-PEROXIDATION-INDUCED DISEASES AND SCREENING METHOD FOR THERAPEUTIC DRUGS FOR LIPID-PEROXIDATION-INDUCED DISEASES | GPX4, GPX1, ALOX15 | PIM1 2199/4885KMT2A 4337/4885MEN1 4562/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.